Publication Name	World Journal of Nephrology
Manuscript ID	24549
Country	New Zealand

Received	2016-01-27 09:43
Peer-Review Started	2016-01-27 15:39
To Make the First Decision	2016-02-29 14:48
Return for Revision	2016-03-04 10:53
Revised	2016-03-17 08:07
Second Decision	2016-04-11 09:08
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-04-22 16:23
Articles in Press	2016-04-22 16:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-06-20 17:25
Publish the Manuscript Online	2016-06-29 09:02

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Urology & Nephrology
Manuscript Type	Retrospective Study
Article Title	Metformin associated lactic acidosis in Auckland City Hospital 2005 to 2009
Manuscript Source	Invited Manuscript
All Author List	Imad Haloob and Janak R de Zoysa
Funding Agency and Grant Number
Corresponding Author	Dr. Janak R de Zoysa, Clinical Director, Department of Renal Medicine, North Shore Hospital, Waitemata District Health Board, 122 Shakespeare Road, Takapuna, Auckland 0740, New Zealand. janak.dezoysa@waitematadhb.govt.nz
Key Words	Acute kidney injury; Lactic acidosis; Metformin
Core Tip	Metformin is an effective therapy for type 2 diabetes mellitus. Although few side effects are described in clinical trials, here, we describe observational evidence that suggests that use of metformin is associated with an increased risk of lactic acidosis. We recommend dose reduction in the elderly, withholding the drug if an intercurrent illness occurs and that metformin be halted in patients with chronic kidney disease G4.
Publish Date	2016-06-29 09:02
Citation	Haloob I, de Zoysa JR. Metformin associated lactic acidosis in Auckland City Hospital 2005 to 2009. World J Nephrol 2016; 5(4): 367-371
URL	http://www.wjgnet.com/2220-6124/full/v5/i4/367.htm
DOI	http://dx.doi.org/10.5527/wjn.v5.i4.367

Full Article (PDF)	WJN-5-367.pdf
Full Article (Word)	WJN-5-367.doc
Manuscript File	24549-Review.doc
Answering Reviewers	24549-Answering reviewers.pdf
Audio Core Tip	24549-Audio core tip.mp3
Biostatistics Review Certificate	24549-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	24549-Conflict-of-interest statement.pdf
Copyright License Agreement	24549-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160127082511.doc
Institutional Review Board Approval Form or Document	24549-Institutional review board statement.pdf
Peer-review Report	24549-Peer-review(s).pdf
Scientific Misconduct Check	24549-Scientific misconduct check.pdf
Scientific Editor Work List	24549-Scientific editor work list.pdf