Publication Name	World Journal of Gastroenterology
Manuscript ID	24571
Country	Mexico

Received	2016-01-30 08:57
Peer-Review Started	2016-01-30 12:13
To Make the First Decision	2016-02-18 10:07
Return for Revision	2016-02-18 11:42
Revised	2016-03-03 03:33
Second Decision	2016-03-11 16:25
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-03-18 17:50
Articles in Press	2016-03-18 17:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-24 16:31
Publish the Manuscript Online	2016-04-29 16:50

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Clinical scenarios for the use of S100β as a marker of hepatic encephalopathy
Manuscript Source	Invited Manuscript
All Author List	Andrés Duarte-Rojo, Astrid Ruiz-Margáin, Ricardo U Macias-Rodriguez, Francisco Javier Cubero, José Estradas-Trujillo, Rosa Ma Muñoz-Fuentes and Aldo Torre
Funding Agency and Grant Number
Corresponding Author	Aldo Torre, MD, MSc, Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Colonia Sección XVI, Tlalpan C.P., México City 14000, Mexico. detoal@yahoo.com
Key Words	Hepatic encephalopathy; S100β protein; Astrocyte; Psychometric hepatic encephalopathy score; Critical flicker frequency
Core Tip	Hepatic encephalopathy is a complication present in 30%-80% of the patients with cirrhosis and it is associated with increased mortality, adverse clinical outcomes, and poor quality of life. An increased concern about early recognition of this complication has risen in recent years; however, no biochemical marker is available to date. In this paper we evaluated the performance of S100β as a biochemical marker to identify the early stages of HE, and its correlation with neuropsychometric tests.
Publish Date	2016-04-29 16:50
Citation	Duarte-Rojo A, Ruiz-Margáin A, Macias-Rodriguez RU, Cubero FJ, Estradas-Trujillo J, Muñoz-Fuentes RM, Torre A. Clinical scenarios for the use of S100β as a marker of hepatic encephalopathy. World J Gastroenterol 2016; 22(17): 4397-4402
URL	http://www.wjgnet.com/1007-9327/full/v22/i17/4397.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i17.4397

Full Article (PDF)	WJG-22-4397.pdf
Full Article (Word)	WJG-22-4397.doc
Manuscript File	24571-Review.docx
Answering Reviewers	24571-Answering reviewers.pdf
Audio Core Tip	24571-Audio core tip.mp3
Biostatistics Review Certificate	24571-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	24571-Conflict-of-interest statement.pdf
Copyright License Agreement	24571-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160130033124.pdf
Institutional Review Board Approval Form or Document	24571-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	24571-Language certificate.pdf
Peer-review Report	24571-Peer-review(s).pdf
Scientific Misconduct Check	24571-Scientific misconduct check.pdf
Scientific Editor Work List	24571-Scientific editor work list.pdf