Publication Name	World Journal of Gastroenterology
Manuscript ID	24671
Country	China

Received	2016-02-12 12:41
Peer-Review Started	2016-02-13 21:11
To Make the First Decision	2016-03-07 08:33
Return for Revision	2016-03-08 16:19
Revised	2016-03-10 19:57
Second Decision	2016-03-17 14:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-03-30 17:04
Articles in Press	2016-03-30 17:05
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-04-10 11:58
Typeset the Manuscript	2016-04-20 17:24
Publish the Manuscript Online	2016-05-17 10:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Plasma long noncoding RNA expression profile identified by microarray in patients with Crohn’s disease
Manuscript Source	Unsolicited Manuscript
All Author List	Dong Chen, Jiang Liu, Hui-Ying Zhao, Yi-Peng Chen, Zun Xiang and Xi Jin
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81370008 National Natural Science Foundation of China 81000169 Natural Science Foundation of Zhejiang Province R2110159 Natural Science Foundation of Zhejiang Province LY15H030006 Natural Science Foundation of Zhejiang Province LY16H030003 Science Technology Project of Zhejiang Province 2014C33205
Corresponding Author	Xi Jin, PhD, Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. jxfl007@zju.edu.cn
Key Words	Crohn’s disease; Long noncoding RNA; Inflammatory bowel disease; Plasma; Microarray
Core Tip	The pathogenesis of Chrohn’s disease (CD) is unclear while increasing evidence supports the involvement of epigenomic regulation. In this study, we jointly used microarray screening and qRT-PCR verification to achieve the plasma specific long noncoding RNAs expression profile of patients with CD and their potential regulation of downstream mRNAs. Our results would provide preliminary data for non-invasive diagnosis of CD and a reservoir for specific lncRNA-mRNA pathway exploration in the future.
Publish Date	2016-05-17 10:45
Citation	Chen D, Liu J, Zhao HY, Chen YP, Xiang Z, Jin X. Plasma long noncoding RNA expression profile identified by microarray in patients with Crohn’s disease. World J Gastroenterol 2016; 22(19): 4716-4731
URL	http://www.wjgnet.com/1007-9327/full/v22/i19/4716.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i19.4716

Full Article (PDF)	WJG-22-4716.pdf
Full Article (Word)	WJG-22-4716.doc
Manuscript File	24671-Review.doc
Answering Reviewers	24671-Answering reviewers.pdf
Audio Core Tip	24671-Audio core tip.wma
Biostatistics Review Certificate	24671-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	24671-Conflict-of-interest statement.pdf
Copyright License Agreement	24671-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	24671-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160211123307.pdf
Institutional Animal Care and Use Committee Approval Form or Document	24671-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	24671-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	24671-Language certificate.pdf
Supplementary Material	Supplementary_Material_20160211123353.jpg
Peer-review Report	24671-Peer-review(s).pdf
Scientific Misconduct Check	24671-Scientific misconduct check.pdf
Scientific Editor Work List	24671-Scientific editor work list.pdf