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Articles Published Processes
6/21/2016 6:11:00 PM | Browse: 981 | Download: 2306
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Received |
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2016-02-01 09:33 |
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Peer-Review Started |
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2016-02-01 10:36 |
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To Make the First Decision |
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2016-03-07 09:34 |
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Return for Revision |
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2016-03-08 10:20 |
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Revised |
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2016-03-30 23:09 |
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Second Decision |
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2016-04-13 07:56 |
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Accepted by Journal Editor-in-Chief |
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2016-04-13 13:11 |
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Accepted by Executive Editor-in-Chief |
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2016-04-20 14:17 |
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Articles in Press |
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2016-04-20 14:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2016-05-05 10:47 |
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Typeset the Manuscript |
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2016-06-06 16:36 |
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Publish the Manuscript Online |
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2016-06-21 18:11 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Effects of sphincter of Oddi motility on the formation of cholesterol gallstones
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhong-Hou Rong, Hong-Yuan Chen, Xin-Xing Wang, Zhi-Yi Wang, Guo-Zhe Xian, Bang-Zhen Ma, Cheng-Kun Qin and Zhen-Hai Zhang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Shandong Province, China |
ZR 2012 HM -07 |
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| Corresponding Author |
Zhen-Hai Zhang, PhD, Department of Hepatobiliary Surgery, Provincial Hospital Affiliated to Shangdong University, No. 324 Jingwuweiqi Road, Jinan 250021, Shandong Province, China. zhangzhenhai410@126.com |
| Key Words |
Cholesterol gallstone; Sphincter of Oddi; Manometry; Myoelectric activity; Cholecystokinin-A receptor |
| Core Tip |
This study investigated the role of sphincter of Oddi (SO) motility in cholesterol gallstone formation in a guinea pig model. The myoelectric activity and manometry of SO were measured at different stages of stone formation. As SO motility is controlled by neurological and hormonal factors, we detected the expression of serum vasoactive intestinal peptide (VIP), gastrin, cholecystokinin octapeptide (CCK-8), and CCK-A receptor (CCKAR) in the SO at different stages of stone formation. We found that a cholesterol gallstone-causing diet can induce SO dysfunction and expression changes of CCKAR in SO smooth muscle and serum VIP and CCK-8 may be important causes of SO dysfunction. |
| Publish Date |
2016-06-21 18:11 |
| Citation |
Rong ZH, Chen HY, Wang XX, Wang ZY, Xian GZ, Ma BZ, Qin CK, Zhang ZH. Effects of sphincter of Oddi motility on the formation of cholesterol gallstones. World J Gastroenterol 2016; 22(24): 5540-5547 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i24/5540.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i24.5540 |
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