Publication Name	World Journal of Clinical Cases
Manuscript ID	24874
Country	Italy

Received	2016-02-12 09:47
Peer-Review Started	2016-02-18 09:16
To Make the First Decision	2016-03-25 14:41
Return for Revision	2016-03-25 18:13
Revised	2016-04-09 00:59
Second Decision	2016-05-10 14:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-05-27 11:09
Articles in Press	2016-05-27 11:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-06-28 14:55
Publish the Manuscript Online	2016-07-07 19:00

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Obstetrics & Gynecology
Manuscript Type	Minireviews
Article Title	Role of urocortin in pregnancy: An update and future perspectives
Manuscript Source	Invited Manuscript
All Author List	Salvatore Giovanni Vitale, Antonio Simone Laganà, Agnese Maria Chiara Rapisarda, Maria Giovanna Scarale, Francesco Corrado, Pietro Cignini, Salvatore Butticè and Diego Rossetti
Funding Agency and Grant Number
Corresponding Author	Antonio Simone Laganà, MD, Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood “G. Barresi”, University of Messina, Via C. Valeria 1, 98125 Messina, Italy. antlagana@unime.it
Key Words	Urocortin; Corticotropin-releasing factor; Obstetrics; Gynecology; Inflammation
Core Tip	Low concentrations of urocortin (UCN) in the amniotic fluid may be a sign of predisposition to preterm birth, since it correlates with a pro-inflammatory state. UCN is present at higher serum concentrations in women with endometriomas. Therefore, the measurement of UCN could be useful in distinguishing between endo-metriosis and other benign ovarian cysts. The thera-peutic treatment with UCN decreases serum levels of proinflammatory cytokines in several experimental situations, so it is plausible that the same effects may occur in different obstetric and gynecological diseases in which inflammation plays a key role in the onset and progression of the disease.
Publish Date	2016-07-07 19:00
Citation	Vitale SG, Laganà AS, Rapisarda AMC, Scarale MG, Corrado F, Cignini P, Butticè S, Rossetti D. Role of urocortin in pre­g­nancy: An update and future perspectives. World J Clin Cases 2016; 4(7): 165-171
URL	http://www.wjgnet.com/2307-8960/full/v4/i7/165.htm
DOI	http://dx.doi.org/10.12998/wjcc.v4.i7.165

Full Article (PDF)	WJCC-4-165.pdf
Full Article (Word)	WJCC-4-165.doc
Manuscript File	24874-Review.docx
Answering Reviewers	24874-Answering reviewers.pdf
Audio Core Tip	24874-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	24874-Conflict-of-interest statement.pdf
Copyright License Agreement	24874-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	24874-Language certificate.pdf
Peer-review Report	24874-Peer-review(s).pdf
Scientific Misconduct Check	24874-Scientific misconduct check.pdf
Scientific Editor Work List	24874-Scientific editor work list.pdf