Publication Name	World Journal of Gastroenterology
Manuscript ID	24955
Country	Japan

Received	2016-02-16 09:33
Peer-Review Started	2016-02-17 18:01
First Decision by Editorial Office Director
Return for Revision	2016-04-01 11:02
Revised	2016-04-11 15:20
Publication Fee Transferred
Second Decision by Editor	2016-04-22 10:29
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2016-05-04 18:31
Articles in Press	2016-05-04 18:31
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-05-10 10:55
Publish the Manuscript Online	2016-06-21 18:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Transient receptor potential vanilloid 4-dependent calcium influx and ATP release in mouse and rat gastric epithelia
Manuscript Source	Invited Manuscript
All Author List	Hiroshi Mihara, Nobuhiro Suzuki, Ammar Abdullkader Boudaka, Jibran Sualeh Muhammad, Makoto Tominaga, Yoshiaki Tabuchi and Toshiro Sugiyama
Funding Agency and Grant Number	Funding Agency Grant Number University of Toyama and JSPS KAKENHI 26870214
Corresponding Author	Hiroshi Mihara, MD, PhD, Assistant Professor, Department of Gastroenterology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. m164-tym@umin.net
Key Words	Transient receptor potential vanilloid 4; Stomach; Gastric emptying; ATP
Core Tip	A mechano-sensitive ion channel, transient receptor potential vanilloid 4 (TRPV4), is expressed in gastric epithelium and contributes to ATP release and gastric emptying. These findings suggest that gastric distension stimulates TRPV4 on gastric epithelium and released ATP stimulates sub-epithelial nerve fibers or acts on visceral smooth muscles. TRPV4 might be a promising novel diagnostic and therapeutic target for functional gastric disorders.
Publish Date	2016-06-21 18:11
Citation	Mihara H, Suzuki N, Boudaka AA, Muhammad JS, Tominaga M, Tabuchi Y, Sugiyama T. Transient receptor potential vanilloid 4-dependent calcium influx and ATP release in mouse and rat gastric epithelia. World J Gastroenterol 2016; 22(24): 5512-5519
URL	http://www.wjgnet.com/1007-9327/full/v22/i24/5512.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i24.5512

Full Article (PDF)	WJG-22-5512.pdf
Full Article (Word)	WJG-22-5512.doc
Manuscript File	24955-Review.docx
Answering Reviewers	24955-Answering reviewers.pdf
Audio Core Tip	24955-Audio core tip.mp3
Biostatistics Review Certificate	24955-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	24955-Conflict-of-interest statement.pdf
Copyright License Agreement	24955-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	24955-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	24955-Language certificate.pdf
Peer-review Report	24955-Peer-review(s).pdf
Scientific Misconduct Check	24955-Scientific misconduct check.pdf
Scientific Editor Work List	24955-Scientific editor work list.pdf