Publication Name	World Journal of Gastroenterology
Manuscript ID	24979
Country	China

Received	2016-02-17 09:14
Peer-Review Started	2016-02-17 09:18
To Make the First Decision	2016-03-07 08:39
Return for Revision	2016-03-08 16:01
Revised	2016-03-16 20:08
Second Decision	2016-03-30 16:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-04-07 16:28
Articles in Press	2016-04-07 16:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-04-19 15:28
Publish the Manuscript Online	2016-05-04 10:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Peer-review started: February 25, 2016
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Combined hepatocellular cholangiocarcinoma: Controversies to be addressed
Manuscript Source	Unsolicited Manuscript
All Author List	An-Qiang Wang, Yong-Chang Zheng, Juan Du, Cheng-Pei Zhu, Han-Chun Huang, Shan-Shan Wang, Liang-Cai Wu, Xue-Shuai Wan, Hao-Hai Zhang, Ruo-Yu Miao, Xin-Ting Sang and Hai-Tao Zhao
Funding Agency and Grant Number
Corresponding Author	Hai-Tao Zhao, MD, Assistant Professor, Chief Doctor, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Shuaifuyuan, Wangfujing, Beijing 100730, China. zhaoht@pumch.cn
Key Words	Progenitor cell origin; Pathology classification; Combined hepatocellular cholangiocarcinoma
Core Tip	This review article focuses on the current views about the histopathology and clinical characteristics of combined hepatocellular cholangiocarcinoma (CHC). Whether the different components of CHC share a common cell origin is still ambiguous. Furthermore, the definition of CHC subtype is still ambiguous and the identification of CHC subtype when a single tumor contains many components has remained unresolved. The features between hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) make CHC has better prognosis than CC but poorer than HCC.
Publish Date	2016-05-04 10:08
Citation	Wang AQ, Zhen YC, Du J, Zhu CP, Huang HC, Wang SS, Wu LC, Wan XS, Zhang HH, Miao RY, Sang XT, Zhao HT. Combined hepatocellular cholangiocarcinoma: Controversies to be addressed. World J Gastroenterol 2016; 22(18): 4459-4465
URL	http://www.wjgnet.com/1007-9327/full/v22/i18/4459.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i18.4459

Full Article (PDF)	WJG-22-4459.pdf
Full Article (Word)	WJG-22-4459.doc
Manuscript File	24979-Review.docx
Answering Reviewers	24979-Answering reviewers.pdf
Audio Core Tip	24979-Audio core tip .wma
Conflict-of-Interest Disclosure Form	24979-Conflict-of-interest statement.pdf
Copyright License Agreement	24979-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	24979-Language certificate.pdf
Peer-review Report	24979-Peer-review(s).pdf
Scientific Misconduct Check	24979-Scientific misconduct check.pdf
Scientific Editor Work List	24979-Scientific editor work list.pdf