Publication Name	World Journal of Hepatology
Manuscript ID	25038
Country	United States

Received	2016-02-20 22:00
Peer-Review Started	2016-02-22 17:38
To Make the First Decision	2016-03-23 11:39
Return for Revision	2016-03-25 17:14
Revised	2016-03-28 23:18
Second Decision	2016-05-27 13:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-06-16 15:17
Articles in Press	2016-06-16 15:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-06-28 16:04
Publish the Manuscript Online	2016-07-13 14:42

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Lipogenesis in Huh7 cells is promoted by increasing the fructose: Glucose molar ratio
Manuscript Source	Invited Manuscript
All Author List	Fernando Windemuller, Jiliu Xu, Simon S Rabinowitz, M Mahmood Hussain and Steven M Schwarz
Funding Agency and Grant Number
Corresponding Author	Steven M Schwarz, MD, Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, State University of New York Downstate Medical Center, 445 Lenox Rd, Box 49, Brooklyn, NY 11203, United States. steven.schwarz@downstate.edu
Key Words	Hepatocytes; Cholesterol; Triglycerides; Fructose; Glucose
Core Tip	Employing an in vitro hepatocyte culture model, these data demonstrate fructose promotes intracellular synthesis both of cholesterol and of trig-lyceride. The results support the requirement for future, in vivo investigations to determine whether diets high in fructose are risk factors for hepatic steatosis and development of non-alcoholic fatty liver disease.
Publish Date	2016-07-13 14:42
Citation	Windemuller F, Xu J, Rabinowitz SS, Hussain MM, Schwarz SM. Lipogenesis in Huh7 cells is promoted by increasing the fructose: Glucose molar ratio. World J Hepatol 2016; 8(20): 838-843
URL	http://www.wjgnet.com/1948-5182/full/v8/i20/838.htm
DOI	http://dx.doi.org/10.4254/wjh.v8.i20.838

Full Article (PDF)	WJH-8-838.pdf
Full Article (Word)	WJH-8-838.doc
Manuscript File	25038-Review.docx
Answering Reviewers	25038-Answering reviewers.pdf
Audio Core Tip	25038-Audio core tip.mp3
Biostatistics Review Certificate	25038-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	25038-Conflict-of-interest statement.pdf
Copyright License Agreement	25038-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	Institutional_Animal_Care_and_Use_Committee_Statement_20160219221644.docx
Institutional Review Board Approval Form or Document	25038-Institutional review board statement.pdf
Peer-review Report	25038-Peer-review(s).pdf
Scientific Misconduct Check	25038-Scientific misconduct check.pdf
Scientific Editor Work List	25038-Scientific editor work list.pdf