Publication Name	World Journal of Gastroenterology
Manuscript ID	2505
Country	China

Received	2013-02-25 18:19
Peer-Review Started	2013-02-27 10:51
To Make the First Decision	2013-03-11 15:08
Return for Revision	2013-03-17 20:08
Revised	2013-04-15 20:45
Second Decision	2013-05-18 16:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-05-19 23:57
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-06-21 08:48
Publish the Manuscript Online	2013-06-28 23:55

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Glycyrrhizic acid attenuates CCl4-induced hepatocyte apoptosis in rats via a p53-mediated pathway
Manuscript Source	Invited Manuscript
All Author List	Xiao-Ling Guo, Bo Liang, Xue-Wei Wang, Fu-Gang Fan, Jing Jin, Rui Lan, Jing-Hui Yang, Xiao-Chun Wang, Lei Jin and Qin Cao
Funding Agency and Grant Number	Funding Agency Grant Number Leading Academic Discipline Project of State Administration of Traditional Chinese Medicine of China
Corresponding Author	Dr. Qin Cao, Department of Gastroenterology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 164 Lanxi Road, Shanghai 200062, China. caoqin434@sina.com
Key Words	P53; Apoptosis; Liver fibrosis; Glycyrrhizic acid; Mitochondria
Core Tip	This study is the first to investigate the effects of glycyrrhizic acid (GA) on p53-dependent apoptosis in carbon tetrachloride (CCl4)-induced hepatic injury. The results indicated that GA can attenuate hepatocyte apoptosis via a p53-mediated mitochondrial pathway and retard the progression of liver fibrosis induced by CCl4 in rats.
Publish Date	2013-06-28 23:55
Citation	Guo XL, Liang B, Wang XW, Fan FG, Jin J, Lan R, Yang JH, Wang XC, Jin L, Cao Q. Glycyrrhizic acid attenuates CCl4-induced hepatocyte apoptosis in rats via a p53-mediated pathway.World J Gastroenterol 2013; 19(24): 3781-3791
URL	http://www.wjgnet.com/1007-9327/full/v19/i24/3781.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i24.3781

Full Article (PDF)	WJG-19-3781.pdf
Manuscript File	2505-Review.doc
Answering Reviewers	2505-Answering reviewers.doc
Copyright License Agreement	2505-Copyright assignment.PDF
Non-Native Speakers of English Editing Certificate	2505-Language certificate.doc
Peer-review Report	2505-Peer review(s).pdf
Scientific Editor Work List	2505-Scientific editor work list.doc