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Articles Published Processes
9/15/2014 8:55:00 PM | Browse: 1409 | Download: 1635
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Received |
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2013-02-25 18:19 |
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Peer-Review Started |
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2013-02-27 10:51 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2013-03-17 20:08 |
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Revised |
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2013-04-15 20:45 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2013-05-18 16:58 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2013-05-19 23:57 |
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Articles in Press |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-06-21 08:48 |
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Publish the Manuscript Online |
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2013-06-28 23:55 |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Autobiography |
| Article Title |
Glycyrrhizic acid attenuates CCl4-induced hepatocyte apoptosis in rats via a p53-mediated pathway
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xiao-Ling Guo, Bo Liang, Xue-Wei Wang, Fu-Gang Fan, Jing Jin, Rui Lan, Jing-Hui Yang, Xiao-Chun Wang, Lei Jin and Qin Cao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Leading Academic Discipline Project of State Administration of Traditional Chinese Medicine of China |
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| Corresponding Author |
Dr. Qin Cao, Department of Gastroenterology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 164 Lanxi Road, Shanghai 200062, China. caoqin434@sina.com
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| Key Words |
P53; Apoptosis; Liver fibrosis; Glycyrrhizic acid; Mitochondria |
| Core Tip |
This study is the first to investigate the effects of glycyrrhizic acid (GA) on p53-dependent apoptosis in carbon tetrachloride (CCl4)-induced hepatic injury. The results indicated that GA can attenuate hepatocyte apoptosis via a p53-mediated mitochondrial pathway and retard the progression of liver fibrosis induced by CCl4 in rats.
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| Publish Date |
2013-06-28 23:55 |
| Citation |
Guo XL, Liang B, Wang XW, Fan FG, Jin J, Lan R, Yang JH, Wang XC, Jin L, Cao Q. Glycyrrhizic acid attenuates CCl4-induced hepatocyte apoptosis in rats via a p53-mediated pathway.World J Gastroenterol 2013; 19(24): 3781-3791 |
| URL |
http://www.wjgnet.com/1007-9327/full/v19/i24/3781.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v19.i24.3781 |
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