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8/3/2016 8:11:00 AM | Browse: 1340 | Download: 1834
Publication Name World Journal of Hepatology
Manuscript ID 25117
Country/Territory Italy
Received
2016-02-23 14:48
Peer-Review Started
2016-02-24 11:32
To Make the First Decision
2016-04-15 08:51
Return for Revision
2016-04-24 09:18
Revised
2016-06-23 00:00
Second Decision
2016-07-15 16:49
Accepted by Journal Editor-in-Chief
2016-07-16 00:38
Accepted by Company Editor-in-Chief
2016-07-22 12:05
Articles in Press
2016-07-22 12:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-07-27 14:22
Publish the Manuscript Online
2016-08-03 08:12
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Boceprevir or telaprevir in hepatitis C virus chronic infection: The Italian real life experience
Manuscript Source Invited Manuscript
All Author List CLEO Study Group; Antonio Ascione, Luigi Elio Adinolfi, Pietro Amoroso, Angelo Andriulli, Orlando Armignacco, Tiziana Ascione, Sergio Babudieri, Giorgio Barbarini, Michele Brogna, Francesco Cesario, Vincenzo Citro, Ernesto Claar, Raffaele Cozzolongo, Giuseppe D’Adamo, Emilio D’Amico, Pellegrino Dattolo, Massimo De Luca, Vincenzo De Maria, Massimo De Siena, Giuseppe De Vita, Antonio Di Giacomo, Rosanna De Marco, Giorgio De Stefano, Giulio De Stefano, Sebastiano Di Salvo, Raffaele Di Sarno, Nunzia Farella, Laura Felicioni, Basilio Fimiani, Luca Fontanella, Giuseppe Foti, Caterina Furlan, Francesca Giancotti, Giancarlo Giolitto, Tiziana Gravina, Barbara Guerrera, Roberto Gulminetti, Angelo Iacobellis, Michele Imparato, Angelo Iodice, Vincenzo Iovinella, Antonio Izzi, Alfonso Liberti, Pietro Leo, Gennaro Lettieri, Ileana Luppino, Aldo Marrone, Ettore Mazzoni, Vincenzo Messina, Roberto Monarca, Vincenzo Narciso, Lorenzo Nosotti, Adriano Maria Pellicelli, Alessandro Perrella, Guido Piai, Antonio Picardi, Paola Pierri, Grazia Pietromatera, Francesco Resta, Luca Rinaldi, Mario Romano, Angelo Rossini, Maurizio Russello, Grazia Russo, Rodolfo Sacco, Vincenzo Sangiovanni, Antonio Schiano, Antonio Sciambra, Gaetano Scifo, Filomena Simeone, Annarita Sullo, Pierluigi Tarquini, Paolo Tundo and Alfredo Vallone
Funding Agency and Grant Number
Corresponding Author Antonio Ascione, MD, Consultant Hepatologist, Department of Medicine, Center for Liver Diseases, “Buon Consiglio” - Fatebenefratelli Hospital, Via A. Manzoni 220, 80126 Naples, Italy. antonio.ascione@paginemediche.it
Key Words Boceprevir; Telaprevir; Chronic hepatitis; Antiviral therapy; Peg-interferon; Ribavirin
Core Tip This study describes the role of antiviral therapy for chronic hepatitis C virus infections in everyday practice. Boceprevir or telaprevir, in com-bination with pegylated interferon and ribavirin, were used in this multicenter study organized by the Italian Association of Hospital Hepatologists (CLEO). A total of 834 patients were enrolled with this first available combination of direct-acting antiviral drugs. The data on the efficacies were quite similar to those produced by the registration studies; however, in the real world experience, patients were older and had more advanced liver disease. In this category of patients, the sustained virological response was less than 50%.
Publish Date 2016-08-03 08:12
Citation CLEO Study Group; Ascione A, Adinolfi LE, Amoroso P, Andriulli A, Armignacco O, Ascione T, Babudieri S, Barbarini G, Brogna M, Cesario F, Citro V, Claar E, Cozzolongo R, D’Adamo G, D’Amico E, Dattolo P, De Luca M, De Maria V, De Siena M, De Vita G, Di Giacomo A, De Marco R, De Stefano G, De Stefano G, Di Salvo S, Di Sarno R, Farella N, Felicioni L, Fimiani B, Fontanella L, Foti G, Furlan C, Giancotti F, Giolitto G, Gravina T, Guerrera B, Gulminetti R, Iacobellis A, Imparato M, Iodice A, Iovinella V, Izzi A, Liberti A, Leo P, Lettieri G, Luppino I, Marrone A, Mazzoni E, Messina V, Monarca R, Narciso V, Nosotti L, Pellicelli AM, Perrella A, Piai G, Picardi A, Pierri P, Pietromatera G, Resta F, Rinaldi L, Romano M, Rossini A, Russello M, Russo G, Sacco R, Sangiovanni V, Schiano A, Sciambra A, Scifo G, Simeone F, Sullo A, Tarquini P, Tundo P, Vallone A. Boceprevir or telaprevir in hepatitis C virus chronic infection: The Italian real life experience. World J Hepatol 2016; 8(22): 949-956
URL http://www.wjgnet.com/1948-5182/full/v8/i22/949.htm
DOI http://dx.doi.org/10.4254/wjh.v8.i22.949
Full Article (PDF) WJH-8-949.pdf
Full Article (Word) WJH-8-949.doc
Manuscript File 25117-Review.docx
Answering Reviewers 25117-Answering reviewers.pdf
Audio Core Tip 25117-Audio core tip.mp3
Biostatistics Review Certificate Biostatistics_Statement_20160223144644.pdf
Conflict-of-Interest Disclosure Form 25117-Conflict-of-interest statement.pdf
Copyright License Agreement 25117-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160223144641.pdf
Institutional Review Board Approval Form or Document 25117-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 25117-Language certificate.pdf
Peer-review Report 25117-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 25117-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 25117-Scientific misconduct check.pdf
Scientific Editor Work List 25117-Scientific editor work list.pdf