Publication Name	World Journal of Gastroenterology
Manuscript ID	25141
Country	South Korea

Received	2016-02-25 09:20
Peer-Review Started	2016-02-25 11:07
To Make the First Decision	2016-03-31 10:08
Return for Revision	2016-03-31 16:30
Revised	2016-04-12 09:19
Second Decision	2016-04-15 15:46
Accepted by Journal Editor-in-Chief	2016-04-16 01:40
Accepted by Executive Editor-in-Chief	2016-04-20 14:13
Articles in Press	2016-04-20 14:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-06-10 19:28
Publish the Manuscript Online	2016-06-21 18:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Basic Study
Article Title	Intravoxel incoherent motion diffusion-weighted imaging for monitoring chemotherapeutic efficacy in gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Li Song, Heoung Keun Kang, Gwang Woo Jeong, Kyu Youn Ahn, Yong Yeon Jeong, Yang Joon Kang, Hye Jung Cho and Chung Man Moon
Funding Agency and Grant Number	Funding Agency Grant Number National Research Foundation of South Korea NRF-2013R1A1A2013878 National Research Foundation of South Korea 2015R1A2A2A01007827
Corresponding Author	Heoung Keun Kang, MD, Professor of Medicine, Department of Radiology, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Hwasun, Jeollanam-do 519-763, South Korea. hkkang@jnu.ac.kr
Key Words	Gastric cancer; Microvessel density; Nude mouse model; Intravoxel incoherent motion diffusion-weighted imaging; Terminal-deoxynucleoitidyl transferase mediated nick end labeling
Core Tip	Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) is useful for monitoring changes of molecular diffusion and microcirculation in gastric cancer at the early stage of chemotherapy. The apparent diffusion coefficient (ADC) and IVIM parameters of true water molecular diffusion coefficient (D) could be reliable marker to detect the necrosis and cellular apoptosis, while perfusion-related IVIM parameters of perfusion fraction (f) and pseudo-related diffusion coefficient (D*) are capable of noninvasive assessment of angiogenesis activity in gastric cancer undergoing chemotherapy.
Publish Date	2016-06-21 18:11
Citation	Song XL, Kang HK, Jeong GW, Ahn KY, Jeong YY, Kang YJ, Cho HJ, Moon CM. Intravoxel incoherent motion diffusion-weighted imaging for monitoring chemotherapeutic efficacy in gastric cancer. World J Gastroenterol 2016; 22(24): 5520-5531
URL	http://www.wjgnet.com/1007-9327/full/v22/i24/5520.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i24.5520

Full Article (PDF)	WJG-22-5520.pdf
Full Article (Word)	WJG-22-5520.doc
Manuscript File	25141-Review.doc
Answering Reviewers	25141-Answering reviews.pdf
Audio Core Tip	25141-Audio core tip.mp3
Biostatistics Review Certificate	25141-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	25141-Conflict-of-interest statement.pdf
Copyright License Agreement	25141-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	25141-Grant application forms.pdf
Institutional Animal Care and Use Committee Approval Form or Document	25141-Institutional animal care and use statement.pdf
Institutional Review Board Approval Form or Document	25141-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	25141-Language certificate.pdf
Peer-review Report	25141-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	25141-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	25141-Scientific misconduct check.pdf
Scientific Editor Work List	25141-Scientific editor work list.pdf