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Articles Published Processes
6/21/2016 6:11:00 PM | Browse: 1125 | Download: 2405
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Received |
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2016-03-04 08:57 |
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Peer-Review Started |
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2016-03-04 14:51 |
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To Make the First Decision |
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2016-04-01 08:06 |
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Return for Revision |
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2016-04-01 17:10 |
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Revised |
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2016-04-10 20:53 |
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Second Decision |
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2016-04-13 07:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-04-20 14:21 |
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Articles in Press |
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2016-04-20 14:21 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2016-05-30 23:49 |
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Typeset the Manuscript |
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2016-06-02 16:58 |
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Publish the Manuscript Online |
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2016-06-21 18:11 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Successful treatment of ileal ulcers caused by immunosuppressants in two organ transplant recipients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yun-Wei Guo, Hua-Ying Gu, Kodjo-Kunale Abassa, Xian-Yi Lin and Xiu-Qing Wei |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Guangdong Science and Technology Program |
2012B061700072 |
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| Corresponding Author |
Xiu-Qing Wei, MD, PhD, Professor, Department of Gastroenterology, the Third Affiliated Hospital of Sun Yat-Sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou 510630, Guangdong Province, China. wei-xiuqing@163.com |
| Key Words |
Ileal ulcers; Liver transplantation; Kidney transplantation; Sirolimus; Tacrolimus |
| Core Tip |
There are few reports available on ileal ulcers caused by immunosuppressants. Herein, we report a liver transplant recipient and a renal transplant recipient who had multiple large ulcers in the distal ileum and ileocecal valve. Ulcers rapidly healed after withdrawal of sirolimus or tacrolimus and administration of thalidomide. No lymphoma, tuberculosis, or infection of cytomegalovirus, Epstein-Barr virus, or fungus was found in either patient. There was no recurrence of ulcers or organ rejection. In some post-transplantation cases with ileal ulcers, sirolimus or tacrolimus should be considered as a risk factor because of their inhibitory effects on wound healing. Withdrawing them or switching to other immunosuppressants might be effective. |
| Publish Date |
2016-06-21 18:11 |
| Citation |
Guo YW, Gu HY, Abassa KK, Lin XY, Wei XQ. Successful treatment of ileal ulcers caused by immunosuppressants in two organ transplant recipients. World J Gastroenterol 2016; 22(24): 5616-5622 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i24/5616.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i24.5616 |
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