Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	25396
Country	Japan

Received	2016-03-07 17:21
Peer-Review Started	2016-03-07 20:41
To Make the First Decision	2016-04-18 19:37
Return for Revision	2016-04-20 15:12
Revised	2016-04-22 14:49
Second Decision	2016-05-09 18:21
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-05-27 11:26
Articles in Press	2016-05-27 11:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-07-25 09:03
Publish the Manuscript Online	2016-08-09 08:50

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Regulation of CTNNB1 signaling in gastric cancer and stem cells
Manuscript Source	Invited Manuscript
All Author List	Shihori Tanabe, Kazuhiko Aoyagi, Hiroshi Yokozaki and Hiroki Sasaki
Funding Agency and Grant Number
Corresponding Author	Shihori Tanabe, PhD, Department of Translational Oncology, National Institute of Health Sciences, 1-18-1, Kami-yoga, Setagaya-ku, Tokyo 158-8501, Japan. stanabe@nihs.go.jp
Key Words	CTNNB1 signaling; b-catenin; Epithelial-mesenchymal transition; Gastric cancer; Stem cell
Core Tip	CTNNB1 signaling is essential for revealing cancer mechanisms. The molecular dynamism in stem cells and cancer is illustrated with a pathway cascade. The CTNNB1 protein interacts with signaling molecules upon stimulation, leading to the transcription of genes related to cell proliferation. Mutations of signaling molecules are also important factors for cancer development. CTNNB1 signaling in stem cells and cancer are mainly described in the article.
Publish Date	2016-08-09 08:50
Citation	Tanabe S, Aoyagi K, Yokozaki H, Sasaki H. Regulation of CTNNB1 signaling in gastric cancer and stem cells. World J Gastrointest Oncol 2016; 8(8): 592-598
URL	http://www.wjgnet.com/1948-5204/full/v8/i8/592.htm
DOI	http://dx.doi.org/10.4251/wjgo.v8.i8.592

Full Article (PDF)	WJGO-8-592.pdf
Full Article (Word)	WJGO-8-592.doc
Manuscript File	25396-Review.doc
Answering Reviewers	25396-Answering reviewers.pdf
Audio Core Tip	25396-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	25396-Conflict-of-interest statement.pdf
Copyright License Agreement	25396-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	25396-Language certificate.pdf
Supplementary Material	Supplementary_Material_20160307171942.pdf
Peer-review Report	25396-Peer-reivew(s).pdf
Scientific Misconduct Check	25396-Scientific misconduct check.pdf
Scientific Editor Work List	25396-Scientific editor work list.pdf