Publication Name	World Journal of Hepatology
Manuscript ID	25662
Country	Canada

Received	2016-03-18 08:46
Peer-Review Started	2016-03-21 18:37
To Make the First Decision	2016-04-15 08:24
Return for Revision	2016-04-19 18:00
Revised	2016-05-06 23:53
Second Decision	2016-07-04 17:07
Accepted by Journal Editor-in-Chief	2016-07-04 17:41
Accepted by Executive Editor-in-Chief	2016-08-01 16:00
Articles in Press	2016-08-01 16:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-09-19 12:29
Publish the Manuscript Online	2016-09-22 09:52

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Implication of the intestinal microbiome in complications of cirrhosis
Manuscript Source	Invited Manuscript
All Author List	Mamatha Bhat, Bianca M Arendt, Venkat Bhat, Eberhard L Renner, Atul Humar and Johane P Allard
Funding Agency and Grant Number
Corresponding Author	Mamatha Bhat, MD, Department of Medicine, University of Toronto, 585 University Avenue, Toronto M5G 2N2, Canada. mamatha.bhat@mail.mcgill.ca
Key Words	Encephalopathy; Intestinal microbiome; Cirrhosis
Core Tip	There has recently been an increasing under-standing of the importance of the intestinal microbiome (IM) in the physiology of cirrhosis and its complications. Novel sequencing techniques have enabled a better characterization of the bacteria in the IM of patients with cirrhosis, and how this differs from the microbiome in a healthy individual. Additionally, therapeutics for enteric dysbiosis in patients with cirrhosis have been studied, and have shown promise in reducing the morbidity of complications in cirrhosis. In this review, we will critically review the literature on characterization of the IM in cirrhosis, its role in com-plications, and the evidence for strategies to address enteric dysbiosis.
Publish Date	2016-09-22 09:52
Citation	Bhat M, Arendt BM, Bhat V, Renner EL, Humar A, Allard JP. Implication of the intestinal microbiome in complications of cirrhosis. World J Hepatol 2016; 8(27): 1128-1136
URL	http://www.wjgnet.com/1948-5182/full/v8/i27/1128.htm
DOI	http://dx.doi.org/10.4254/wjh.v8.i27.1128

Full Article (PDF)	WJH-8-1128.pdf
Full Article (Word)	WJH-8-1128.doc
Manuscript File	25662-Review.docx
Answering Reviewers	25662-Answering reviewers.pdf
Audio Core Tip	25662-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	25662-Conflict-of-interest statement.pdf
Copyright License Agreement	25662-Copyright assignment.pdf
Peer-review Report	25662-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	25662-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	25662-Scientific misconduct check.pdf
Scientific Editor Work List	25662-Scientific editor work list.pdf