Publication Name	World Journal of Gastroenterology
Manuscript ID	25720
Country	Spain

Received	2016-03-20 16:37
Peer-Review Started	2016-03-22 18:19
To Make the First Decision	2016-03-31 09:52
Return for Revision	2016-04-01 15:26
Revised	2016-04-15 09:28
Second Decision	2016-04-28 09:28
Accepted by Journal Editor-in-Chief	2016-04-30 15:57
Accepted by Executive Editor-in-Chief	2016-05-04 18:45
Articles in Press	2016-05-04 18:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-05-16 17:02
Publish the Manuscript Online	2016-05-30 17:40

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	How important is donor age in liver transplantation?
Manuscript Source	Invited Manuscript
All Author List	Alberto Lué, Estela Solanas, Pedro Baptista, Sara Lorente, Juan J Araiz, Agustin Garcia-Gil and M Trinidad Serrano
Funding Agency and Grant Number
Corresponding Author	M Trinidad Serrano, MD, PhD (Med), Liver Transplantation Unit, Department of Gastroenterology, University Hospital Lozano Blesa, C/San Juan Bosco 15, 50009 Zaragoza, Spain. utra.hcu@salud.aragon.es
Key Words	Liver transplantation; Liver regeneration; Graft survival; Old donor; Aging
Core Tip	Because of a donor shortage, the use of grafts from old donors has become widespread. Donor age is related to worse outcomes after liver transplantation, higher rates of graft failure, biliary complications and a worse graft survival. In recipients with hepatitis C, the impact of donor age is even more evident. Aging-related changes at the hepatocellular level may contribute to a decreased capacity of the liver to manage or overcome liver diseases and injuries. This review summarizes the evidence regarding the impact of donor age on liver transplantation outcomes.
Publish Date	2016-05-30 17:40
Citation	Lué A, Solanas E, Baptista P, Lorente S, Araiz JJ, Garcia-Gil A, Serrano MT. How important is donor age in liver transplantation? World J Gastroenterol 2016; 22(21): 4966-4976
URL	http://www.wjgnet.com/1007-9327/full/v22/i21/4966.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i21.4966

Full Article (PDF)	WJG-22-4966.pdf
Full Article (Word)	WJG-22-4966.doc
Manuscript File	25720-Review.docx
Answering Reviewers	25720-Answering reviewers.pdf
Audio Core Tip	25720-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	25720-Conflict-of-interest statement.pdf
Copyright License Agreement	25720-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	25720-Language certificate.pdf
Peer-review Report	25720-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	25720-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	25720-Scientific misconduct check.pdf
Scientific Editor Work List	25720-Scientific editor work list.pdf