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Articles Published Processes
7/15/2016 3:38:00 PM | Browse: 1339 | Download: 2887
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Received |
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2016-03-22 15:44 |
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Peer-Review Started |
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2016-03-23 11:18 |
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To Make the First Decision |
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2016-04-14 10:09 |
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Return for Revision |
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2016-04-14 14:26 |
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Revised |
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2016-05-19 00:00 |
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Second Decision |
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2016-05-23 08:45 |
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Accepted by Journal Editor-in-Chief |
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2016-05-26 05:46 |
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Accepted by Executive Editor-in-Chief |
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2016-06-15 18:35 |
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Articles in Press |
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2016-06-15 18:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-07-08 10:13 |
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Publish the Manuscript Online |
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2016-07-15 15:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Immunohistochemistry panel segregates molecular types of hepatocellular carcinoma in Brazilian autopsy cases
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Aloísio Felipe-Silva, Alda Wakamatsu, Cinthya dos Santos Cirqueira and Venâncio Avancini Ferreira Alves |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fundação de Amparo a Pesquisa do Estado de São Paulo |
08/58855-3 to Alves VAF |
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| Corresponding Author |
Aloísio Felipe-Silva, MD, PhD, LIM 14-Patologia Hepática, Faculdade de Medicina da USP, Avenida Dr. Arnaldo 455 1o. Andar Sala 1157, 01246-903 São Paulo SP, Brazil. aloisiosilva@hu.usp.br
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| Key Words |
Hepatocellular carcinoma; Epidermal growth factor receptor; Autopsy; Immunohistochemistry; Liver; Classification |
| Core Tip |
This study assessed the immunohistochemistry-detected expression of several protein products of genes known to be involved in the molecular pathogenesis of hepatocellular carcinoma (HCC) in a retrospective autopsy cohort of patients with HCC. The data showed that expression profiles of these markers may be related to different pathways underlying HCC progression and metastasis, and that the Edmondson-Steiner’s tumor grade may reflect currently recognized molecular subclasses of HCC. This cross-sectional analysis supports the strategy of translating genomic data into panels of immunohistochemical markers for risk evaluation in HCC and also reinforces the paramount importance of histological grade in this context.
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| Publish Date |
2016-07-15 15:38 |
| Citation |
Felipe-Silva A, Wakamatsu A, dos Santos Cirqueira C, Alves VAF. Immunohistochemistry panel segregates molecular types of hepatocellular carcinoma in Brazilian autopsy cases. World J Gastroenterol 2016; 22(27): 6246-6256 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i27/6246.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i27.6246 |
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