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Articles Published Processes
11/10/2016 9:27:00 AM | Browse: 1419 | Download: 1777
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Received |
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2016-03-24 08:48 |
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Peer-Review Started |
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2016-03-25 13:52 |
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To Make the First Decision |
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2016-05-13 16:28 |
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Return for Revision |
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2016-05-14 11:28 |
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Revised |
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2016-07-16 18:48 |
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Second Decision |
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2016-09-02 10:58 |
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Accepted by Journal Editor-in-Chief |
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2016-09-02 14:03 |
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Accepted by Executive Editor-in-Chief |
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2016-09-08 16:18 |
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Articles in Press |
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2016-09-08 16:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-11-03 15:09 |
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Publish the Manuscript Online |
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2016-11-10 09:27 |
ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Review |
Article Title |
Nutrition, insulin resistance and dysfunctional adipose tissue determine the different components of metabolic syndrome
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Manuscript Source |
Invited Manuscript |
All Author List |
Juan Antonio Paniagua |
Funding Agency and Grant Number |
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Corresponding Author |
Juan Antonio Paniagua, PhD, Insulin Resistance, Metabolism and Adipose Tissue Unit, Maimonides Institute of Biomedical Research, University Hospital Reina Sofia, Avda Menendez Pidal, s/n, 14004 Cordoba, Spain. japaniaguag@yahoo.es |
Key Words |
Obesity; Metabolic syndrome; Metabolism; Adipokines; Insulin resistance; Lipotoxicity and nutrition |
Core Tip |
Central obesity, the insulin resistance, hyperglycemia, hypertriglyceridemia, hypoalphalipoproteinemia, hypertension and fatty liver are grouped in the so-called metabolic syndrome (MetS). In subjects with MetS an energy balance is critical to maintain a healthy body weight, mainly limiting the intake of high energy density foods. However, high-carbohydrate rich (CHO) diets increase postprandial peaks of insulin and glucose. Triglyceride-rich lipoproteins are also increased, which interferes with reverse cholesterol transport lowering high-density lipoprotein cholesterol. In addition, CHO-rich diets could move fat from peripheral to central deposits and reduce adiponectin activity in peripheral adipose tissue. All these are improved with monounsaturated fatty acid-rich diets. Lastly, increased portions of ω-3 and ω-6 fatty acids also decrease triglyceride levels, and complement the healthy diet that is recommended in patients with MetS. |
Publish Date |
2016-11-10 09:27 |
Citation |
Paniagua JA. Nutrition, insulin resistance and dysfunctional adipose tissue determine the different components of metabolic syndrome. World J Diabetes 2016; 7(19): 483-514 |
URL |
http://www.wjgnet.com/1948-9358/full/v7/i19/483.htm |
DOI |
http://dx.doi.org/10.4239/wjd.v7.i19.483 |
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