Publication Name	World Journal of Critical Care Medicine
Manuscript ID	2585
Country	United States

Received	2013-03-01 19:43
Peer-Review Started	2013-03-03 17:47
To Make the First Decision	2013-03-18 15:48
Return for Revision	2013-03-22 14:40
Revised
Second Decision	2014-03-04 09:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-04 10:15
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-08 20:23
Publish the Manuscript Online	2014-05-20 21:40

ISSN	2220-3141(online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Critical Care Medicine
Manuscript Type	Autobiography
Article Title	Arterial vs venous blood gas differences during hemorrhagic shock
Manuscript Source	Invited Manuscript
All Author List	Kristopher Burton Williams, Ashley Britton Christmas, Brant Todd Heniford, Ronald Fong Sing and Joseph Messick
Funding Agency and Grant Number	Funding Agency Grant Number Carolinas HealthCare System, Department of Surgery, Charlotte, North Carolina, United States
Corresponding Author	Ronald Fong Sing, DO, FACS, FCCM, Department of Surgery, Carolinas HealthCare System, 1000 Blythe Boulevard, Charlotte, NC 28203, United States. ron.sing@carolinashealthcare.org
Key Words	Hemorrhagic shock; pH; Base deficit; Arterial blood gases; Venous blood gases
Core Tip	Recent studies regarding early goal directed therapy and damage control resuscitation have indicated a potential role for calculated arteriovenous pCO2 differences in monitoring resuscitative efforts. In a rabbit model of hemorrhagic shock, we demonstrate significant derangements between arterial and venous blood and, while not a novel concept, explore the potential of central venous pCO2 as an indicator of hemorrhagic shock. Our results demonstrate a widened arteriovenous pCO2 difference is significantly associated with hemorrhagic shock and may be a more reliable indicator of inadequate tissue perfusion and therefore impending circulatory collapse.
Publish Date	2014-05-20 21:40
Citation	Williams KB, Christmas AB, Heniford BT, Sing RF, Messick J. Arterial vs venous blood gas differences during hemorrhagic shock. World J Crit Care Med 2014; 3(2): 55-60
URL	http://www.wjgnet.com/2220-3141/full/v3/i2/55.htm
DOI	http://dx.doi.org/10.5492/wjccm.v3.i2.55

Full Article (PDF)	WJCCM-3-55.pdf
Full Article (Word)	WJCCM-3-55.doc
Manuscript File	2585-Review.doc
Copyright License Agreement	2585-Copyright assignment.pdf
Peer-review Report	2585-Peer reviews.pdf
Scientific Editor Work List	2585-Scientific editor work list.doc