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3/9/2017 4:09:00 PM | Browse: 338 | Download: 367
Publication Name World Journal of Diabetes
Manuscript ID 25901
Country of Manuscript Source Japan
Received
2016-03-26 16:47
Peer-Review Started
2016-03-26 21:11
To Make the First Decision
2016-05-13 16:30
Return for Revision
2016-05-14 19:53
Revised
2016-08-31 10:23
Second Decision
2016-12-26 11:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-01-14 14:50
Articles in Press
2017-01-14 14:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-03-07 09:28
Publish the Manuscript Online
2017-03-09 16:09
ISSN 1948-9358 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biology
Manuscript Type Minireviews
Article Title Involvement of Cbl-b-mediated macrophage inactivation in insulin resistance
Manuscript Source Invited Manuscript
All Author List Tomoki Abe, Katsuya Hirasaka and Takeshi Nikawa
Funding Agency and Grant Number
Funding Agency Grant Number
the Japan Society for the Promotion of Science KAKENHI to Tomoki Abe JP15K16208
Corresponding author Takeshi Nikawa, MD, PhD, Professor, Department of Nutritional Physiology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan. nikawa@tokushima-u.ac.jp
Keywords Casitas b-lineage lymphoma-b; Insulin resistance; Macrophage; Obesity; Toll-like receptor 4
Core Tip Obesity leads to the development of chronic inflammation and insulin resistance (IR). Adipose tissue macrophages (ATMs) play a crucial role in the development of obesity-induced IR. Therefore, ATMs are attractive therapeutic targets for IR. Recently, we demonstrated that the ubiquitin ligase Casitas b-lineage lymphoma-b (Cbl-b) negatively regulates the migration and activation of ATMs. Here, we review key aspects of Cbl-b function in the regulation of ATMs.
Publish Date 2017-03-09 16:09
Citation Abe T, Hirasaka K, Nikawa T. Involvement of Cbl-b-mediated macrophage inactivation in insulin resistance. World J Diabetes 2017; 8(3): 97-103
Url http://www.wjgnet.com/1948-9358/full/v8/i3/97.htm
DOI http://dx.doi.org/10.4239/wjd.v8.i3.97
Full Article (PDF) WJD-8-97.pdf
Full Article (Word) WJD-8-97.doc
Manuscript File 25901-Review.docx
Answering Reviewers 25901-Answering reviewers.pdf
Audio Core Tip 25901-Audio core tip.wav
Conflict-of-Interest Disclosure Form 25901-Conflict-of-interest statement.pdf
Copyright License Agreement 25901-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 25901-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 25901-Language certificate.pdf
Peer-review Report 25901-Peer-review(s).pdf
Scientific Misconduct Check 25901-Scientific misconduct check.pdf
Scientific Editor Work List 25901-Scientific editor work list.pdf