Publication Name	World Journal of Gastroenterology
Manuscript ID	25938
Country	United States

Received	2016-03-26 15:30
Peer-Review Started	2016-03-26 22:23
To Make the First Decision	2016-05-12 14:32
Return for Revision	2016-05-13 08:51
Revised	2016-05-28 03:58
Second Decision	2016-06-06 08:23
Accepted by Journal Editor-in-Chief	2016-06-07 13:42
Accepted by Company Editor-in-Chief	2016-06-15 18:56
Articles in Press	2016-06-15 18:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-06-27 17:15
Publish the Manuscript Online	2016-07-15 15:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Aberrant post-translational protein modifications in the pathogenesis of alcohol-induced liver injury
Manuscript Source	Invited Manuscript
All Author List	Natalia A Osna, Wayne G Carter, Murali Ganesan, Irina A Kirpich, Craig J McClain, Dennis R Petersen, Colin T Shearn, Maria L Tomasi and Kusum K Kharbanda
Funding Agency and Grant Number
Corresponding Author	Kusum K Kharbanda, PhD, Research Service, Veterans Affairs Nebraska-Western Iowa Health Care System, Research Service (151), 4101 Woolworth Avenue, Omaha, Ne 68105, United States. kkharbanda@unmc.edu
Key Words	Alcohol; Acetylation; Liver; Carbonylation methylation; Dysfunction; Methylation; Glycosylation; Phosphorylation; Ubiquitination; Sumoylation; Betaine; Post-translational protein modification
Core Tip	A majority of proteins in our body undergo orchestrated post-translational modifications that influence protein structure and function. Chronic ethanol administration causes aberrant post-trans-lational modification of proteins that play a critical role in the pathogenesis of alcoholic-induced liver damage.
Publish Date	2016-07-15 15:38
Citation	Osna NA, Carter WG, Ganesan M, Kirpich IA, McClain CJ, Petersen DR, Shearn CT, Tomasi ML, Kharbanda KK. Aberrant post-translational protein modifications in the pathogenesis of alcohol-induced liver injury. World J Gastroenterol 2016; 22(27): 6192-6200
URL	http://www.wjgnet.com/1007-9327/full/v22/i27/6192.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i27.6192

Full Article (PDF)	WJG-22-6192.pdf
Full Article (Word)	WJG-22-6192.doc
Manuscript File	25938-Review.docx
Answering Reviewers	25938-Answering reviewers.pdf
Audio Core Tip	25938-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	25938-Conflict-of-interest statement.pdf
Copyright License Agreement	25938-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	25938-Grant application form(s).pdf
Supplementary Material	25938-Supplemental Table 1.xlsx
Peer-review Report	25938-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	25938-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	25938-Scientific misconduct check.pdf
Scientific Editor Work List	25938-Scientific editor work list.pdf