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Articles Published Processes
9/26/2016 8:04:00 AM | Browse: 1356 | Download: 2414
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Received |
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2016-03-28 15:30 |
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Peer-Review Started |
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2016-03-28 17:33 |
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To Make the First Decision |
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2016-05-12 14:29 |
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Return for Revision |
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2016-05-13 09:02 |
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Revised |
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2016-05-28 12:05 |
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Second Decision |
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2016-06-06 08:20 |
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Accepted by Journal Editor-in-Chief |
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2016-06-07 15:18 |
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Accepted by Executive Editor-in-Chief |
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2016-06-15 19:02 |
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Articles in Press |
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2016-06-15 19:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2016-08-16 12:16 |
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Typeset the Manuscript |
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2016-09-09 14:28 |
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Publish the Manuscript Online |
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2016-09-26 08:04 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Regulation of the serotonin transporter in the pathogenesis of irritable bowel syndrome
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Duo-Chen Jin, Hai-Long Cao, Meng-Que Xu, Si-Nan Wang, Yu-Ming Wang, Fang Yan and Bang-Mao Wang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81300272 (to Cao HL) |
| National Natural Science Foundation of China |
81470796 (to Yan F) |
| National Natural Science Foundation of China |
81570489 (to Wang YM) |
| National Natural Science Foundation of China |
No. 81570478 (to Wang BM) |
| Tianjin Research Program of Application Foundation and Advanced Technology of China |
15JCZDJC36600 (to Yan F) |
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| Corresponding Author |
Hai-Long Cao, MD, PhD, Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, 154 Anshan Road, Heping District, Tianjin 300052, China. cao_hailong@163.com |
| Key Words |
Irritable bowel syndrome; Serotonin; Serotonin transporter; Regulation; Therapy |
| Core Tip |
The serotonin transporter (SERT) participates in metabolizing serotonin in the gut and plays a crucial role in the pathogenesis of irritable bowel syndrome (IBS). This review summarizes the relevant evidence on the factors that might regulate SERT, including SERT gene polymorphisms, microRNAs, immunity and inflammation, gut microbiota and growth factors. This review also reveals several potential treatments targeting SERT for IBS patients. |
| Publish Date |
2016-09-26 08:04 |
| Citation |
Jin DC, Cao HL, Xu MQ, Wang SN, Wang YM, Yan F, Wang BM. Regulation of the serotonin transporter in the pathogenesis of irritable bowel syndrome. World J Gastroenterol 2016; 22(36): 8137-8148 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i36/8137.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i36.8137 |
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