Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	26023
Country	China

Received	2016-03-28 13:39
Peer-Review Started	2016-03-28 14:07
To Make the First Decision	2016-05-17 12:19
Return for Revision	2016-05-18 11:34
Revised	2016-06-02 16:23
Second Decision	2016-06-13 16:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-06-29 10:01
Articles in Press	2016-06-29 10:01
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-07-08 11:15
Typeset the Manuscript	2016-08-27 17:33
Publish the Manuscript Online	2016-09-12 14:59

ISSN	1948-5190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Surgery
Manuscript Type	Minireviews
Article Title	Laparoscopic splenectomy for primary immune thrombocytopenia: Current status and challenges
Manuscript Source	Invited Manuscript
All Author List	Dong Zheng, Chen-Song Huang, Shao-Bin Huang and Chao-Xu Zheng
Funding Agency and Grant Number	Funding Agency Grant Number Science and Technique Project of Guangdong Province 2012B031800284
Corresponding Author	Chao-Xu Zheng, MD, PhD, Professor of Surgery, Department of Pancreato-biliary Surgery, the First Affiliated Hospital of Sun Yat-sen University, 58 Zhongshan 2 Road, Guangzhou 510080, Guangdong Province, China. zhengchaoxu@yahoo.com
Key Words	Laparoscopic splenectomy; Corticosteroids; Open splenectomy; Hematological outcome; Predictor; Biomarker; Immune thrombocytopenia
Core Tip	Despite the new drugs developed to treat primary immune thrombocytopenia, splenectomy is still the main therapy for patients who fail corticosteroid treatment. Laparoscopic splenectomy proves to be a preferable technique compared to open splenectomy. The response rate to splenectomy should be reassessed based on the unified outcome criteria by current international consensus. So far, there are not widely accepted preo-perative indicators predicting response to laparoscopic splenectomy. The challenge facing the doctors is to identify a reliable predictor of long-term outcome of splenectomy which can help make the decision of operation.
Publish Date	2016-09-12 14:59
Citation	Zheng D, Huang CS, Huang SB, Zheng CX. Laparoscopic splenectomy for primary immune thrombocytopenia: Current status and challenges. World J Gastrointest Endosc 2016; 8(17): 610-615
URL	http://www.wjgnet.com/1948-5190/full/v8/i17/610.htm
DOI	http://dx.doi.org/10.4253/wjge.v8.i17.610

Full Article (PDF)	WJGE-8-610.pdf
Full Article (Word)	WJGE-8-610.doc
Manuscript File	26023-Review.docx
Answering Reviewers	26023-Answering reviewers.pdf
Audio Core Tip	26023-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	26023-Conflict-of-interest statement.pdf
Copyright License Agreement	26023-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	26023-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	26023-Language certificate.pdf
Peer-review Report	26023-Peer-review(s).pdf
Scientific Misconduct Check	26023-Scientific misconduct check.pdf
Scientific Editor Work List	26023-Scientific editor work list.pdf