Publication Name	World Journal of Gastroenterology
Manuscript ID	26034
Country	China

Received	2016-03-28 09:38
Peer-Review Started	2016-03-28 15:30
To Make the First Decision	2016-05-30 09:20
Return for Revision	2016-05-30 13:00
Revised	2016-06-12 07:30
Second Decision	2016-06-23 17:26
Accepted by Journal Editor-in-Chief	2016-06-24 07:06
Accepted by Company Editor-in-Chief	2016-07-06 18:38
Articles in Press	2016-07-06 18:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-07-26 09:13
Publish the Manuscript Online	2016-07-29 20:32

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Inflammatory microenvironment contributes to epithelial-mesenchymal transition in gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Hui-Ying Ma, Xin-Zhou Liu and Chun-Min Liang
Funding Agency and Grant Number	Funding Agency Grant Number National Science Foundation of China 3147114
Corresponding Author	Chun-Min Liang, MD, PhD, Lab of Tumor Immunology, Department of Anatomy and Histology and Embryology, Shanghai Medical College of Fudan University, 138 Yixueyuan Road, Shanghai 200032, China. cmliang@fudan.edu.cn
Key Words	Gastric cancer; Inflammation; Epithelial-mesenchymal transition; Microenvironment; Immune cells
Core Tip	The major cause of gastric cancer (GC) is Helicobacter pylori infection, resulting in an inflam-matory microenvironment in GC. Meanwhile, the leading cause of death for GC patients is metastasis. The major pathway for metastasis is the epithelial-mesenchymal transition (EMT). Therefore, a thorough understanding of how the inflammatory microenvironment contributes to the promotion of the EMT is indispensable for develo-ping new treatments. In this review, we summarize the mechanisms of inflammatory mediators, divided among immune cells and molecules, on the prognosis of GC patients and EMT, which suggests that a combination of immunotherapy and anti-EMT treatments may be encouraging for the treatment of GC.
Publish Date	2016-07-29 20:32
Citation	Ma HY, Liu XZ, Liang CM. Inflammatory microenvironment contributes to epithelial-mesenchymal transition in gastric cancer. World J Gastroenterol 2016; 22(29): 6619-6628
URL	http://www.wjgnet.com/1007-9327/full/v22/i29/6619.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i29.6619

Full Article (PDF)	WJG-22-6619.pdf
Full Article (Word)	WJG-22-6619.doc
Manuscript File	26034-Review.docx
Answering Reviewers	26034-Answering reviewers.pdf
Audio Core Tip	26034-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	26034-Conflict-of-interest statement.pdf
Copyright License Agreement	26034-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	26034-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	26034-Language certificate.pdf
Peer-review Report	26034-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	26034-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	26034-Scientific misconduct check.pdf
Scientific Editor Work List	26034-Scientific editor work list.pdf