Publication Name	World Journal of Gastroenterology
Manuscript ID	26055
Country	Iran

Received	2016-03-28 08:37
Peer-Review Started	2016-03-29 14:43
To Make the First Decision	2016-05-30 09:21
Return for Revision	2016-05-30 13:06
Revised	2016-06-13 16:18
Second Decision	2016-07-08 08:48
Accepted by Journal Editor-in-Chief	2016-07-10 22:15
Accepted by Executive Editor-in-Chief	2016-07-21 16:04
Articles in Press	2016-07-21 16:04
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-09-12 13:34
Typeset the Manuscript	2016-10-13 12:33
Publish the Manuscript Online	2016-10-20 17:06

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Topic Highlights
Article Title	Update on occult hepatitis B virus infection
Manuscript Source	Invited Manuscript
All Author List	Manoochehr Makvandi
Funding Agency and Grant Number
Corresponding Author	Dr. Manoochehr Makvandi, Health Research Institute, Infectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Sciences, Boulevard Golestan, Ahvaz 15794-61357, Iran. manoochehrmakvandi29@yahoo.com
Key Words	Nested polymerase chain reaction; Occult hepatitis B infection; Cryptogenic; Real-time polymerase chain reaction
Core Tip	Occult hepatitis B infection (OBI) is defined as negative hepatitis B surface antigen and positive/negative anti-hepatitis B core immunoglobulin G status but hepatitis B virus (HBV) DNA is detectable in serum and liver tissue. Genotypes A, C, G, E and D have been found among patients with OBI in different regions of the world. Genotype D is the only dominant genotype among Iranian OBI patients. OBI has been reported among many high risk groups, including blood donors, liver transplant recipients, patients co-infected with hepatitis C virus/human immunodeficiency virus, patients undergoing immunosuppressive therapy or hemodialysis, patients with liver cirrhosis, cryptogenic liver disease, or abnormal alanine transaminase, healthcare workers, patients with lymphoma or rheumatoid arthritis. It is recommended that to manage and reduce OBI and HBV carriage, the screening of HBV DNA be implemented among high risk groups by means of highly sensitive molecular assays periodically. In addition, comprehensive investigations are needed to understand the epidemiology of OBI worldwide.
Publish Date	2016-10-20 17:06
Citation	Makvandi M. Update on occult hepatitis B virus infection. World J Gastroenterol 2016; 22(39): 8720-8734
URL	http://www.wjgnet.com/1007-9327/full/v22/i39/8720.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i39.8720

Full Article (PDF)	WJG-22-8720.pdf
Full Article (Word)	WJG-22-8720.doc
Manuscript File	26055-Review.doc
Answering Reviewers	26055-Answering reviewers.pdf
Audio Core Tip	26055-Audio core tip.mp3
Copyright License Agreement	26055-Copyright assignment.pdf
Peer-review Report	26055-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	26055-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	26055-Scientific misconduct check.pdf
Scientific Editor Work List	26055-Scientific editor work list.pdf