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Articles Published Processes
9/4/2016 2:49:00 PM | Browse: 1234 | Download: 2062
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Received |
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2016-03-30 10:11 |
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Peer-Review Started |
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2016-04-05 09:29 |
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To Make the First Decision |
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2016-05-30 09:21 |
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Return for Revision |
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2016-05-30 14:10 |
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Revised |
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2016-06-27 22:03 |
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Second Decision |
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2016-07-21 18:37 |
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Accepted by Journal Editor-in-Chief |
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2016-07-21 22:31 |
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Accepted by Executive Editor-in-Chief |
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2016-08-01 15:52 |
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Articles in Press |
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2016-08-01 15:53 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-08-24 21:56 |
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Publish the Manuscript Online |
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2016-09-04 14:49 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was
selected by an in-house editor and fully peer-reviewed by external
reviewers. It is distributed in accordance with the Creative
Commons Attribution Non Commercial (CC BY-NC 4.0) license,
which permits others to distribute, remix, adapt, build upon this
work non-commercially, and license their derivative works on
different terms, provided the original work is properly cited and
the use is non-commercial. See: http://creativecommons.org/
licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2016. Published by Baishideng Publishing
Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Infectious Diseases |
Manuscript Type |
Prospective Study |
Article Title |
Dried blood spots, valid screening for viral hepatitis and human immunodeficiency virus in real-life
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Manuscript Source |
Invited Manuscript |
All Author List |
Belinda K Mössner, Benjamin Staugaard, Janne Jensen, Søren Thue Lillevang, Peer B Christensen and Dorte Kinggaard Holm |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
an unrestricted grant from Abbvie, Denmark |
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Corresponding Author |
Peer B Christensen, PhD, Associate Professor, Department of Infectious Diseases, Odense University Hospital, Sdr. Boulevard 29, DK 5000 Odense C,
Denmark. peer.christensen@dadlnet.dk |
Key Words |
Dried blood spot; Real-life; Screening; Hepatitis B; Hepatitis C; Human immunodeficiency virus; People who inject drugs; Drug-users; Prisoners |
Core Tip |
This study shows that it is feasible to combine serology and nucleic acid screening for hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections in one dried blood sample (DBS) collected in real life and analyzed using a modern laboratory platform. We observed a sensitivity and specificity of > 96% for HBV, HCV, and HIV and correctly classified 95% of all HCV patients into past vs chronic infections compared to simultaneously collected venous blood samples. The study confirms that DBSs are feasible samples in outreach clinics and confirms the high sensitivity and specificity of previous laboratory-based studies. |
Publish Date |
2016-09-04 14:49 |
Citation |
Mössner BK, Staugaard B, Jensen J, Lillevang ST, Christensen PB, Holm DK. Dried blood spots, valid screening for viral hepatitis and human immunodeficiency virus in real-life. World J Gastroenterol 2016; 22(33): 7604-7612 |
URL |
http://www.wjgnet.com/1007-9327/full/v22/i33/7604.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v22.i33.7604 |
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