| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Hepatitis C virus G1b infection decreases the number of small low-density lipoprotein particles
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chika Kinoshita, Tomohisa Nagano, Nobuyoshi Seki, Yoichi Tomita, Tomonori Sugita, Yuta Aida, Munenori Itagaki, Kenichi Satoh, Satoshi Sutoh, Hiroshi Abe, Akihito Tsubota and Yoshio Aizawa |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shionogi Pharmaceutical KK |
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| Corresponding Author |
Chika Kinoshita, MD, Department of Gastroenterology and Hepatology, Internal Medicine of Jikei University Katsushika Medical Center, 6-41-2 Aoto, Katsushikaku, Tokyo 125-8506, Japan. c.kinoshita.3678@gmail.com |
| Key Words |
Chronic hepatitis C; Lipoprotein particles; Low-density lipoproteins; Very low-density lipoproteins; Triglycerides; Cholesterol; Regression analysis |
| Core Tip |
Hepatitis C virus (HCV) infection was pre-viously reported to alter the serum lipid and lipoprotein profiles. However, the effect of HCV on the number of lipoprotein particles was not previously examined because counting the number of lipoprotein particles is challenging. In this report, we investigated how HCV infection changes the particle number of lipoproteins and demonstrated that HCV infection independently decreased the numbers of medium, small, and very small low-density lipoprotein particles. This finding may provide a new perspective on the association between HCV infection and atherosclerosis. |
| Publish Date |
2016-07-29 20:32 |
| Citation |
Kinoshita C, Nagano T, Seki N, Tomita Y, Sugita T, Aida Y, Itagaki M, Satoh K, Sutoh S, Abe H, Tsubota A, Aizawa Y. Hepatitis C virus G1b infection decreases the number of small low-density lipoprotein particles. World J Gastroenterol 2016; 22(29): 6716-6725 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i29/6716.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i29.6716 |
