Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	26289
Country	South Africa

Received	2016-04-02 10:20
Peer-Review Started	2016-04-06 15:39
First Decision by Editorial Office Director
Return for Revision	2016-05-17 17:17
Revised	2016-05-26 16:24
Publication Fee Transferred
Second Decision by Editor	2016-05-27 17:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2016-06-03 16:28
Articles in Press	2016-06-03 16:28
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-01 16:02
Publish the Manuscript Online	2016-08-07 21:31

ISSN	2219-2808 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Developmental Biology
Manuscript Type	Observational Study
Article Title	Hypothesis on supine sleep, sudden infant death syndrome reduction and association with increasing autism incidence
Manuscript Source	Invited Manuscript
All Author List	Nils J Bergman
Funding Agency and Grant Number
Corresponding Author	Dr. Nils J Bergman, MB ChB, MPH, MD, School of Child and Adolescent Health, University of Cape Town, Private Bag X3, Rondebosch 7700, South Africa. nils@ninobirth.org
Key Words	Autism; Autism spectrum disorder; Incidence; Prevalence; Prone sleep; Sudden infant death syndrome; Supine sleep; Time trends
Core Tip	An earlier article presents evidence that supine sleep is a stressor, with sympathetic arousal that protects infants with defects in auto-resuscitation from sudden infant death syndrome. This article argues that a possible side-effect in the population being subjected to supine sleep is an increase in the expression of features contributing to diagnosis of autism spectrum disorder. In a literature search, five countries were identified (Denmark, United Kingdom, Australia, Israel, United States) with published time trends of autism, and with change-points coinciding with supine sleep campaigns. The stressor hypothesis for both conditions are amenable to testing, a better understanding of both is likely to improve outcomes.
Publish Date	2016-08-07 21:31
Citation	Bergman NJ. Hypothesis on supine sleep, sudden infant death syndrome reduction and association with increasing autism incidence. World J Clin Pediatr 2016; 5(3): 330-342
URL	http://www.wjgnet.com/2219-2808/full/v5/i3/330.htm
DOI	http://dx.doi.org/10.5409/wjcp.v5.i3.330

Full Article (PDF)	WJCP-5-330.pdf
Full Article (Word)	WJCP-5-330.doc
Manuscript File	26289-Review.doc
Answering Reviewers	26289-Answering reviewers.pdf
Audio Core Tip	26289-Audio core tip.m4a
Biostatistics Review Certificate	26289-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	26289-Conflict-of-interest statement.pdf
Copyright License Agreement	26289-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	26289-Institutional review board statement.pdf
Peer-review Report	26289-Peer-review(s).pdf
Scientific Misconduct Check	26289-Scientific misconduct check.pdf
Scientific Editor Work List	26289-Scientific editor work list.pdf