BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/14/2016 11:03:00 AM | Browse: 1146 | Download: 1732
 |
Received |
|
2016-04-05 09:07 |
|
Peer-Review Started |
|
2016-04-05 14:29 |
|
To Make the First Decision |
|
2016-05-17 12:20 |
|
Return for Revision |
|
2016-05-18 11:36 |
|
Revised |
|
2016-06-29 00:00 |
|
Second Decision |
|
2016-07-12 13:02 |
|
Accepted by Journal Editor-in-Chief |
|
2016-07-12 17:10 |
|
Accepted by Executive Editor-in-Chief |
|
2016-07-22 12:14 |
|
Articles in Press |
|
2016-07-22 12:14 |
 |
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2016-07-30 08:32 |
|
Typeset the Manuscript |
|
2016-09-12 19:40 |
|
Publish the Manuscript Online |
|
2016-09-14 11:03 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Predictive potential of <i>IL-28B</i> genetic testing for interferon based hepatitis C virus therapy in Pakistan: Current scenario and future perspective
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Muhammad Sohail Afzal |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Muhammad Sohail Afzal, PhD, Department of Chemistry, School of Science, University of Management and Technology, C-Ⅱ Johar Town, Lahore 54000, Pakistan. sohail.ncvi@gmail.com |
| Key Words |
Diagnostics; Hepatitis C virus; Interferon therapy; Polymorphisms; <i>IL-28B</i>; Genetic testing; Pakistan |
| Core Tip |
Pakistan has a very heavy burden of hepatitis C virus (HCV) infection with around 11 million positive cases; however, in spite of well established prognostic value, the data regarding the role of interleukin 28B (<i>IL-28B</i>) single nucleotide polymorphisms (SNPs) in HCV antiviral therapy response are very limited. There are only six reports on the topic and it can be concluded from this limited information that <i>IL-28B</i> could be a good prognosis marker for HCV patient management in Pakistan. The major prevalent HCV genotype in Pakistan is 3a and <i>IL-28B</i> SNP rs12979860 showed a good prediction for interferon based antiviral therapy response against this viral genotype. It can be pre-dicted that inclusion of <i>IL-28B</i> genetic testing in routine diagnostic set-up of Pakistan will help in better management of the disease. A well directed antiviral therapy based on personalized <i>IL-28B</i> genotyping along with virus genotyping will help in lessening of therapy cost and better management of the disease. |
| Publish Date |
2016-09-14 11:03 |
| Citation |
Afzal MS. Predictive potential of <i>IL-28B</i> genetic testing for interferon based hepatitis C virus therapy in Pakistan: Current scenario and future perspective. World J Hepatol 2016; 8(26): 1116-1118 |
| URL |
http://www.wjgnet.com/1948-5182/full/v8/i26/1116.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v8.i26.1116 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
