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Articles Published Processes
7/4/2016 2:42:00 PM | Browse: 1344 | Download: 2232
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Received |
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2016-04-06 09:01 |
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Peer-Review Started |
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2016-04-06 09:51 |
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To Make the First Decision |
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2016-05-12 10:24 |
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Return for Revision |
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2016-05-12 15:29 |
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Revised |
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2016-05-13 13:26 |
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Second Decision |
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2016-06-01 18:55 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-06-02 15:35 |
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Articles in Press |
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2016-06-02 15:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2016-06-20 18:18 |
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Typeset the Manuscript |
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2016-06-23 12:17 |
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Publish the Manuscript Online |
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2016-07-04 14:42 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Allergy |
| Manuscript Type |
Observational Study |
| Article Title |
Low expression of ARID1A correlates with poor prognosis in intrahepatic cholangiocarcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Song-Zhu Yang, An-Qiang Wang, Juan Du, Jian-Tao Wang, Wei-Wei Yu, Qing Liu, Yan-Fang Wu and Shu-Guang Chen |
| Funding Agency and Grant Number |
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| Corresponding Author |
Shu-Guang Chen, MD, Professor, Department of Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China. pumchcsg@163.com |
| Key Words |
ARID1A; Intrahepatic cholangiocarcinoma; Progression; Prognosis; Biomarker |
| Core Tip |
We investigated the relationship between ARID1A expression and clinicopathologic parameters, as well as its prognostic value, for patients with intrahepatic cholangiocarcinoma (IHCC). We examined ARID1A protein and mRNA expression in IHCC and paracarcinomatous (PC) tissue from 57 patients with IHCC. The mean ARID1A protein and mRNA expression levels in IHCC tissues were significantly lower than those in PC tissues and normal liver tissues. Low ARID1A expression was significantly associated with tumor nodules, vein invasion, and recurrence. Low ARID1A expression was significantly associated with worse overall survival in multivariate analyses. ARID1A may be a potential prognostic biomarker candidate in IHCC.
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| Publish Date |
2016-07-04 14:42 |
| Citation |
Yang SZ, Wang AQ, Du J, Wang JT, Yu WW, Liu Q, Wu YF, Chen SG. Low expression of ARID1A correlates with poor prognosis in intrahepatic cholangiocarcinoma. World J Gastroenterol 2016; 22(25): 5814-5821 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i25/5814.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i25.5814 |
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