Publication Name	World Journal of Diabetes
Manuscript ID	2640
Country	United Kingdom

Received	2013-03-05 10:02
Peer-Review Started	2013-03-05 15:23
To Make the First Decision	2013-03-25 15:19
Return for Revision	2013-04-07 09:24
Revised	2013-04-14 04:46
Second Decision	2013-04-18 16:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-04-19 06:08
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-04-23 01:25
Typeset the Manuscript	2013-05-31 19:40
Publish the Manuscript Online	2013-06-20 15:18

ISSN	1948-9358 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Gastrointestinal complications of diabetes mellitus
Manuscript Source	Invited Manuscript
All Author List	Babu Krishnan, Shithu Babu, Jessica Walker, Adrian B Walker and Joseph M Pappachan
Funding Agency and Grant Number
Corresponding Author	Dr. Joseph M Pappachan, MD, MRCP, Department of Endocrinology, University Hospital of North Staffordshire NHS Trust, Princes Rd, Stoke-on-Trent ST4 6QG, United Kingdom. drpappachan@yahoo.co.in
Key Words	Gastrointestinal complications; Diabetes mellitus; Esophageal complications; Nonalcoholic fatty liver disease; Diabetic gastroparesis; Diabetic enteropathy; Glycogenic hepatopathy
Core Tip	Although relatively common, gastrointestinal (GI) complications of diabetes mellitus are under-recognized by most physicians. Early identification and prompt management of GI complications are of paramount importance as they are associated with significant morbidity. Common GI complications are esophageal dysmotility, gastro-esophageal reflux disease, gastroparesis, enteropathy, non alcoholic fatty liver disease (NAFLD) and glycogenic hepatopathy. Damage to the myenteric neurons due to longstanding diabetes causes esophageal, gastric and enteric disease. NAFLD is a hepatic manifestation of metabolic syndrome and is commonly seen in type 2 diabetes while glycogenic hepatopathy is due to poor glycemic control in type 1 diabetes. Clinical manifestations, pathogenesis, diagnostic evaluation and management of GI complications of diabetes are discussed in this article.
Publish Date	2013-06-20 15:18
Citation	Krishnan B, Babu S, Walker J, Walker AB, Pappachan JM. Gastrointestinal complications of diabetes mellitus. World J Diabetes 2013; 4(3): 51-63
URL	http://www.wjgnet.com/1948-9358/full/v4/i3/51.htm
DOI	http://dx.doi.org/10.4239/wjd.v4.i3.51

Full Article (PDF)	WJD-4-51.pdf
Manuscript File	2640-Review.doc
Answering Reviewers	2640-Answering reviewers.pdf
Copyright License Agreement	2640-Copyright assignment.pdf
Peer-review Report	2640-Peer reviews.pdf
Scientific Editor Work List	2640-Scientific editor work list.doc