Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	26481
Country	United States

Received	2016-04-11 17:11
Peer-Review Started
To Make the First Decision	2016-04-11 17:59
Return for Revision	2016-04-20 15:12
Revised	2016-05-08 00:15
Second Decision	2016-06-01 17:29
Accepted by Journal Editor-in-Chief	2016-06-02 05:53
Accepted by Executive Editor-in-Chief	2016-06-16 14:48
Articles in Press	2016-06-16 14:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-07-20 09:03
Publish the Manuscript Online	2016-08-01 11:49

ISSN	2150-5349 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Response of irritable bowel syndrome with constipation patients administered a combined quebracho/conker tree/M. balsamea Willd extract
Manuscript Source	Unsolicited Manuscript
All Author List	Kenneth Brown, Brandi Scott-Hoy and Linda W Jennings
Funding Agency and Grant Number
Corresponding Author	Brandi Scott-Hoy, MD, KBS Research LLC, 15660 N Dallas Parkway, Suite 700, Dallas, TX 75248, United States. brandi@kbsresearch.com
Key Words	Irritable bowel syndrome; Constipation; Abdominal pain; Bloating; Dietary supplement; Herbal; Botanical; Extract; Peppermint
Core Tip	Irritable bowel syndrome with constipation (IBS-C) is a diagnosis by exclusion which is defined by abdominal pain accompanied by reduced stool frequency and painful, hard bowel movements. Gas and bloating may also be present in many patients with this condition suggesting a role in fermentation of food producing gas by bacteria in the gut. Safe tannin byproducts from wineries used in cows to reduce gas that can impair milk and meat production are combined with saponins, shown to be antibacterial and promote intestinal motility, and peppermint oil for abdominal pain in this combination extract (Atrantil?) to manage key IBS-C symptoms.
Publish Date	2016-08-01 11:49
Citation	Brown K, Scott-Hoy B, Jennings LW. Response of irritable bowel syndrome with constipation patients administered a combined quebracho/conker tree/M. balsamea Willd extract. World J Gastrointest Pharmacol Ther 2016; 7(3): 463-468
URL	http://www.wjgnet.com/2150-5349/full/v7/i3/463.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v7.i3.463

Full Article (PDF)	WJGPT-7-463.pdf
Full Article (Word)	WJGPT-7-463.doc
Manuscript File	26481-Review.docx
Answering Reviewers	26481-Answering review(s).pdf
Audio Core Tip	26481-Audio core tip.wav
Conflict-of-Interest Disclosure Form	26481-Conflict-of-interest statement.pdf
Copyright License Agreement	26481-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	26481-Institutional review board statement.pdf
Supplementary Material	Supplementary_Material_20160411171038.docx
Peer-review Report	26481-Peer-reivew(s).pdf
Scientific Misconduct Check	26481-Scientific misconduct check.pdf
Scientific Editor Work List	26481-Scientific editor work list.pdf