Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	26483
Country	Portugal

Received	2016-04-12 09:10
Peer-Review Started	2016-04-13 18:28
To Make the First Decision	2016-07-20 16:52
Return for Revision	2016-07-22 14:56
Revised	2016-08-07 02:02
Second Decision	2016-09-05 09:44
Accepted by Journal Editor-in-Chief	2016-09-05 23:25
Accepted by Executive Editor-in-Chief	2016-09-18 14:20
Articles in Press	2016-09-18 14:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-10-24 14:26
Publish the Manuscript Online	2016-10-31 09:01

ISSN	2150-5349 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Osteonecrosis of both knees in a woman with Crohn's disease
Manuscript Source	Unsolicited Manuscript
All Author List	Mara Barbosa and José Cotter
Funding Agency and Grant Number
Corresponding Author	Mara Barbosa, MD, Department of Gastroenterology, Hospital da Senhora da Oliveira, Creixomil, 4835-044 Guimarães, Portugal. maraisabelbarbosa@net.sapo.pt
Key Words	Osteonecrosis; Knee; Inflammatory bowel disease; Crohn’s disease; Magnetic resonance imaging
Core Tip	Although very rare, osteonecrosis is a devasting event that can occur in Crohn’s disease (CD). We present the case of a 22 years old woman with CD who was diagnosed with osteonecrosis of both knees. As we demonstrate with this report, awareness of risk factors, such as corticosteroid therapy and inflammatory bowel disease activity, is crucial to establish the diagnosis of this inflammatory bowel disease rheumatological complication. Prompt treatment is recommended. A review of the literature is also presented.
Publish Date	2016-10-31 09:01
Citation	Barbosa M, Cotter J. Osteonecrosis of both knees in a woman with Crohn’s disease. World J Gastrointest Pharmacol Ther 2016; 7(4): 579-583
URL	http://www.wjgnet.com/2150-5349/full/v7/i4/579.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v7.i4.579

Full Article (PDF)	WJGPT-7-579.pdf
Full Article (Word)	WJGPT-7-579.doc
Manuscript File	26483-Review.docx
Answering Reviewers	26483-Answering reviewers.pdf
Audio Core Tip	26483-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	26483-Conflict-of-interest statement.pdf
Copyright License Agreement	26483-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160411182642.pdf
Institutional Review Board Approval Form or Document	26483-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	26483-Language certificate.pdf
Peer-review Report	26483-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	26483-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	26483-Scientific misconduct check.pdf
Scientific Editor Work List	26483-Scientific editor work list.pdf