Publication Name	World Journal of Clinical Oncology
Manuscript ID	26628
Country	Japan

Received	2016-04-20 14:39
Peer-Review Started	2016-04-22 09:50
To Make the First Decision	2016-06-06 10:35
Return for Revision	2016-06-12 15:27
Revised	2016-07-11 20:00
Second Decision	2016-08-22 13:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-08-31 12:16
Articles in Press	2016-08-31 12:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-09-28 13:16
Publish the Manuscript Online	2016-10-08 16:54

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Granulocyte colony-stimulating factor-producing hepatocellular carcinoma with abrupt changes
Manuscript Source	Invited Manuscript
All Author List	Hiroaki Nagata, Shuhei Komatsu, Wataru Takaki, Tokunari Okayama, Yasunori Sawabe, Michiaki Ishii, Mitsuo Kishimoto, Eigo Otsuji and Hiroshi Konosu
Funding Agency and Grant Number
Corresponding Author	Shuhei Komatsu, MD, Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, 465 Kawaramachihirokoji, Kamigyo-ku, Kyoto 602-0855, Japan. skomatsu@koto.kpu-m.ac.jp
Key Words	Granulocyte colony stimulating factor; Granulocyte colony-stimulating factor producing tumor; Hepatocellular carcinoma; Immunohistochemistry; Sarcomatous changes
Core Tip	Granulocyte colony-stimulating factor (G-CSF)-producing tumor is one of the rare types of cancer clinically characterized by an elevated fever and white blood cell increment. Although G-CSF producing tumors have been reported in several types of cancer including those of the lungs, cervix and bladder, G-CSF producing hepatocellular carcinoma (HCC) is extremely rare. This is the 9th case report of G-CSF producing HCC in English literature. We report our case and review reported literatures with special reference to the clinical characteristics of the G-CSF producing HCC and a possible treatment strategy.
Publish Date	2016-10-08 16:54
Citation	Nagata H, Komatsu S, Takaki W, Okayama T, Sawabe Y, Ishii M, Kishimoto M, Otsuji E, Konosu H. Granulocyte colony-stimulating factor-producing hepatocellular carcinoma with abrupt changes. World J Clin Oncol 2016; 7(5): 380-386
URL	http://www.wjgnet.com/2218-4333/full/v7/i5/380.htm
DOI	http://dx.doi.org/10.5306/wjco.v7.i5.380

Full Article (PDF)	WJCO-7-380.pdf
Full Article (Word)	WJCO-7-380.doc
Manuscript File	26628-Review.docx
Answering Reviewers	26628-Answering reviewers.pdf
Audio Core Tip	26628-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	26628-Conflict-of-interest statement.pdf
Copyright License Agreement	26628-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160419104434.pdf
Non-Native Speakers of English Editing Certificate	26628-Language certificate.pdf
Peer-review Report	26628-Peer-review(s).pdf
Scientific Misconduct Check	26628-Scientific misconduct check.pdf
Scientific Editor Work List	26628-Scientific editor work list.pdf