Publication Name	World Journal of Gastroenterology
Manuscript ID	26709
Country	United States

Received	2016-04-23 16:04
Peer-Review Started	2016-04-23 17:29
To Make the First Decision	2016-05-27 14:57
Return for Revision	2016-05-28 13:52
Revised	2016-06-09 02:11
Second Decision	2016-06-28 09:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-07-06 18:32
Articles in Press	2016-07-06 18:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-22 16:10
Publish the Manuscript Online	2016-09-04 14:49

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/ licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Surgery
Manuscript Type	Systematic Reviews
Article Title	Mechanistic insights of rapid liver regeneration after associating liver partition and portal vein ligation for stage hepatectomy
Manuscript Source	Unsolicited Manuscript
All Author List	Demetrios Moris, Spyridon Vernadakis, Alexandros Papalampros, Michail Vailas, Nikolaos Dimitrokallis, Athanasios Petrou and Dimitrios Dimitroulis
Funding Agency and Grant Number
Corresponding Author	Demetrios Moris, MD, PhD, Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Ave., NE60, Cleveland, OH 44195, United States. dimmoris@yahoo.com
Key Words	Liver regeneration; Associating liver partition with portal vein ligation for staged hepatectomy; Portal vein embolization; Portal vein ligation; Liver transection
Core Tip	It seems that liver regeneration after asso-ciating liver partition with portal vein ligation for staged hepatectomy (ALPPS) is a combination of portal flow changes and parenchymal transection that generate a systematic response inducing hepatocyte proliferation and remodeling. Further research on the field should focus on the role of non-parenchymal cells as well as on the effect of ALPPS in liver regeneration in the setup of parenchymal liver disease.
Publish Date	2016-09-04 14:49
Citation	Moris D, Vernadakis S, Papalampros A, Vailas M, Dimitrokallis N, Petrou A, Dimitroulis D. Mechanistic insights of rapid liver regeneration after associating liver partition and portal vein ligation for stage hepatectomy. World J Gastroenterol 2016; 22(33): 7613-7624
URL	http://www.wjgnet.com/1007-9327/full/v22/i33/7613.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i33.7613

Full Article (PDF)	WJG-22-7613.pdf
Full Article (Word)	WJG-22-7613.doc
Manuscript File	26709-Review.doc
Answering Reviewers	26709-Answering reviewers.pdf
Audio Core Tip	26709-Audio core tip.wav
Conflict-of-Interest Disclosure Form	26709-Conflict-of-interest statement.pdf
Copyright License Agreement	26709-Copyright assignment.pdf
Supplementary Material	Supplementary_Material_20160423032315.pdf
Peer-review Report	26709-Peer-review(s).pdf
Scientific Misconduct Check	26709-Scientific misconduct check.pdf
Scientific Editor Work List	26709-Scientific editor work list.pdf