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8/1/2016 9:43:00 AM | Browse: 99 | Download: 143
Publication Name World Journal of Clinical Oncology
Manuscript ID 26720
Country of Manuscript Source Greece
Received
2016-04-23 15:17
Peer-Review Started
2016-04-23 20:47
To Make the First Decision
2016-06-06 10:42
Return for Revision
2016-06-07 10:38
Revised
2016-06-15 15:44
Second Decision
2016-07-15 16:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-07-22 12:07
Articles In Press
2016-07-22 12:07
Publication Fee Transferred
Edit the Manuscript by Languag Editor
Typeset the Manuscript
2016-07-26 15:12
Publish the Manuscript Online
2016-08-01 09:43
ISSN 2218-4333 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Specialty Obstetrics and Gynecology
Manuscript Type Systematic Review
Article Title Sorafenib in breast cancer treatment: A systematic review and overview of clinical trials
Manuscript Source Invited Manuscript
All Author List Menelaos Zafrakas, Panayiota Papasozomenou and Christos Emmanouilides
Funding Agency and Grant Number
Correspondence To Menelaos Zafrakas, FEBS (Breast Surgery), Professor of Obstetrics and Gynecology, Research Laboratory for Mastology, Gynecology and Obstetrics, School of Health and Medical Care, Alexander Technological Institute of Thessaloniki, Ethnikis Antistaseos 81, 57400 Thessaloniki, Greece. mzafrakas@gmail.com
Keywords Breast cancer; Sorafenib; Kinase inhibitors; BRAF; Mitogen-activated protein kinase
Core Tip In this systematic review of the literature, the role of sorafenib in the treatment of breast cancer has been evaluated. Regarding toxicity, sorafenib was generally well tolerated in breast cancer patients, while in terms of efficacy the most promising results came from clinical trials evaluating sorafenib in combination with gemcitabine and/or capecitabine and possibly tamoxifen. Efficacy was inadequate with sorafenib monotherapy and combinations with taxanes, bevacizumab and ixabepilone.
Publish Date 2016-08-01 09:43
Citation Zafrakas M, Papasozomenou P, Emmanouilides C. Sorafenib in breast cancer treatment: A systematic review and overview of clinical trials. World J Clin Oncol 2016; 7(4): 331-336
Url http://www.wjgnet.com/2218-4333/full/v7/i4/331.htm
DOI http://dx.doi.org/10.5306/wjco.v7.i4.331
Full Article (PDF) WJCO-7-331.pdf
Full Article (Word) WJCO-7-331.doc
Revised Manuscript 26720-Review.docx
Peer-review Report 26720-Peer-review(s).pdf
Answering Reviewers 26720-Answering reviewers.pdf
Scientific Misconduct Check 26720-Scientific misconduct check.pdf
Scientific Editor Work List 26720-Scientific editor work list.pdf
Audio 26720-Audio core tip.mp3
Conflict-of-Interest Statement 26720-Conflict-of-interest statement.pdf
Copyright Assignment 26720-Copyright assignment.pdf
Data Sharing Statement 26720-Data sharing statement.pdf