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Articles Published Processes
10/25/2016 8:46:00 AM | Browse: 1369 | Download: 3060
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Received |
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2016-04-24 19:33 |
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Peer-Review Started |
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2016-04-25 15:13 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2016-06-07 11:05 |
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Revised |
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2016-06-25 14:23 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2016-08-19 12:20 |
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Second Decision by Editor-in-Chief |
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2016-08-22 15:54 |
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Final Decision by Editorial Office Director |
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2016-08-29 11:24 |
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Articles in Press |
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2016-08-29 11:24 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-10-20 17:36 |
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Publish the Manuscript Online |
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2016-10-25 08:46 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Tropical Medicine |
| Manuscript Type |
Prospective Study |
| Article Title |
Regulatory and activated effector T cells in chronic hepatitis C virus: Relation to autoimmunity
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hanan Fouad, Maissa El Raziky, Eman Medhat Hassan, Ghada Mahmoud Abdel Aziz, Samar K Darweesh and Ahmed Reda Sayed |
| Funding Agency and Grant Number |
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| Corresponding Author |
Hanan Fouad, Professor, Department of Medical Biochemistry, Faculty of Medicine, Cairo University, 110 Manial Street, Manial El-Roda District, Cairo 11562,
Egypt. hanan.fouad@kasralainy.edu.eg |
| Key Words |
Autoimmunity; T regulatory cells; Hepatitis C virus; T activator cells; Interferon |
| Core Tip |
A prospective study conducted on 120 subjects divided into: Treatment naïve hepatitis C virus (HCV) patients, HCV patients treated with old standard of care, HCV associated with antinuclear antibody (ANA) and healthy control group. Teffs/Tregs imbalance was evaluated. Results showed that HCV patients exhibited significant higher levels of both Teffs and Tregs markers. Interferon-α and ribavirin therapy suppresses proliferation of Tregs. More significant suppression of Tregs was observed in HCV patients with autoanti-bodies favoring pathological autoimmune response. Teffs markers were significantly elevated in HCV treated group and in HCV group with ANA +ve in comparison to treatment naïve HCV group.
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| Publish Date |
2016-10-25 08:46 |
| Citation |
Fouad H, El Raziky M, Hassan EM, Aziz GMA, Darweesh SK, Sayed AR. Regulatory and activated effector T cells in chronic hepatitis C virus: Relation to autoimmunity. World J Hepatol 2016; 8(30): 1287-1294 |
| URL |
http://www.wjgnet.com/1948-5182/full/v8/i30/1287.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v8.i30.1287 |
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