Publication Name	World Journal of Meta-Analysis
Manuscript ID	26762
Country	United Kingdom

Received	2016-04-26 10:23
Peer-Review Started	2016-04-26 16:11
To Make the First Decision	2016-06-12 09:16
Return for Revision	2016-06-16 10:56
Revised	2016-06-28 21:48
Second Decision	2016-07-05 17:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-07-18 10:46
Articles in Press	2016-07-18 10:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-25 11:06
Publish the Manuscript Online	2016-08-26 20:47

ISSN	2308-3840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Infectious Diseases
Manuscript Type	Meta-Analysis
Article Title	Antibiotics for eradicating meningococcal carriages: Network meta-analysis and investigation of evidence inconsistency
Manuscript Source	Invited Manuscript
All Author List	Asmaa S Abdelhamid, Yoon K Loke, Ibrahim Abubakar and Fujian Song
Funding Agency and Grant Number	Funding Agency Grant Number UK Medical Research Council G0701607
Corresponding Author	Fujian Song, PhD, Professor, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, United Kingdom. fujian.song@uea.ac.uk
Key Words	Chemoprophylaxis; Antibiotics; Nersseria meningitidis; Meningococcal infection; Network meta-analysis
Core Tip	This network meta-analysis found that a range of prophylactic antibiotic regimens are effective for eradicating meningococcal carriages. A combination of rifampin and minocycline seems the most efficacious, and ceftriaxone is also likely to be more effective than ciprofloxacin or rifampin alone. Careful investigation of significant inconsistency between direct and indirect comparison of rifampin and ciprofloxacin found that it was mainly caused by different types of carriers (persistent or any) and the varying doses of ciprofloxacin in the included trials. Detailed examination of chara-cteristics of relevant studies should be con-ducted for investigating causes of inconsistency in net-work meta-analysis.
Publish Date	2016-08-26 20:47
Citation	Abdelhamid AS, Loke YK, Abubakar I, Song F. Antibiotics for eradicating meningococcal carriages: Network meta-analysis and investigation of evidence inconsistency. World J Meta-Anal 2016; 4(4): 77-87
URL	http://www.wjgnet.com/2308-3840/full/v4/i4/77.htm
DOI	http://dx.doi.org/10.13105/wjma.v4.i4.77

Full Article (PDF)	WJMA-4-77.pdf
Full Article (Word)	WJMA-4-77.doc
Manuscript File	26762-Review.docx
Answering Reviewers	26762-Answering reviewers.pdf
Audio Core Tip	26762-Audio core tip.m4a
Biostatistics Review Certificate	26762-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	26762-Conflict-of-interest statement.pdf
Copyright License Agreement	26762-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	26762-Grant application form(s).pdf
Peer-review Report	26762-Peer-review(s).pdf
Scientific Misconduct Check	26762-Scientific misconduct check.pdf
Scientific Editor Work List	26762-Scientific editor work list.pdf