Publication Name	World Journal of Respirology
Manuscript ID	26786
Country	United States

Received	2016-04-27 11:41
Peer-Review Started	2016-04-27 17:13
First Decision by Editorial Office Director
Return for Revision	2016-06-17 17:32
Revised	2016-07-20 04:11
Publication Fee Transferred
Second Decision by Editor	2016-08-08 15:27
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2016-08-18 11:45
Articles in Press	2016-08-18 11:45
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-11-21 08:51
Publish the Manuscript Online	2016-11-24 14:41

ISSN	2218-6255 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Pulmonary complications of transcatheter arterial chemoembolization for hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Quan M Nhu, Harry Knowles, Paul J Pockros and Catherine T Frenette
Funding Agency and Grant Number	Funding Agency Grant Number NIH 4KL2TR001112 (to Quan M Nhu)
Corresponding Author	Catherine T Frenette, MD, Scripps Center for Organ Transplantation, Scripps Clinic - Scripps Green Hospital, 10666 N. Torrey Pines Rd, Suite N200, La Jolla, CA 92037, United States. frenette.catherine@scrippshealth.org
Key Words	Transcatheter arterial chemoembolization; Liver cirrhosis; Pulmonary complications; Hepatocellular carcinoma; Acute lung injury; Acute respiratory distress syndrome; Pneumonitis; Pulmonary oil embolism
Core Tip	Pulmonary complications after transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) are thought to be related to chemical injury caused by the infused ethiodized oil or chemo-therapeutic agent, which can migrate to the lung vasculature via arteriovenous (AV) shunts associated with the hyper-vascular HCC. The risk factors associated with post-TACE pulmonary complications include large hyper-vascular HCC, AV shunts, large volume of Lipiodol, and embolization via the right inferior phrenic artery. However, the absence of known risk factors is not a guarantee against serious complications. Careful monitoring of patients perioperatively and an awareness of the potential post-TACE pulmonary complications should expedite early recognition and effective manage-ment of these patients.
Publish Date	2016-11-24 14:41
Citation	Nhu QM, Knowles H, Pockros PJ, Frenette CT. Pulmonary complications of transcatheter arterial chemoembolization for hepatocellular carcinoma. World J Respirol 2016; 6(3): 69-75
URL	http://www.wjgnet.com/2218-6255/full/v6/i3/69.htm
DOI	http://dx.doi.org/10.5320/wjr.v6.i3.69

Full Article (PDF)	WJR-6-69.pdf
Full Article (Word)	WJR-6-69.doc
Manuscript File	26786-Review.docx
Answering Reviewers	26786-Answering reviewers.pdf
Audio Core Tip	26786-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	26786-Conflict-of-interest statement.pdf
Copyright License Agreement	26786-Copyright assignment.pdf
Peer-review Report	26786-Peer-review(s).pdf
Scientific Misconduct Check	26786-Scientific misconduct check.pdf
Scientific Editor Work List	26786-Scientific editor work list.pdf