Publication Name	World Journal of Gastroenterology
Manuscript ID	26804
Country	United Kingdom

Received	2016-04-27 10:28
Peer-Review Started	2016-04-27 11:29
To Make the First Decision	2016-05-30 09:22
Return for Revision	2016-05-30 14:56
Revised	2016-06-10 01:07
Second Decision	2016-06-23 17:28
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-07-06 18:53
Articles in Press	2016-07-06 18:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-12 17:35
Publish the Manuscript Online	2016-08-24 10:09

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Pancreatic cancer: Are "liquid biopsies" ready for prime-time?
Manuscript Source	Invited Manuscript
All Author List	Alexandra R Lewis, Juan W Valle and Mairead G McNamara
Funding Agency and Grant Number
Corresponding Author	Dr. Mairead G McNamara, The Christie NHS Foundation Trust, 550 Wilmslow Road, M20 4BX Manchester, United Kingdom. mairead.mcnamara@christie.nhs.uk
Key Words	Pancreatic; Cancer; Liquid biopsy; Circulating; Tumour; Cells; Circulating tumour DNA
Core Tip	Pancreatic cancer is a difficult disease to diagnose and treat. Persistently poor outcomes mean that new biomarkers of disease and treatments are required. Circulating tumour cells and circulating tumour DNA have been investigated as liquid biopsies in pancreatic cancer. Sensitivity is variable but speci?ficity promising. The most effective platform and most informative biomarkers are yet to be identified. There are many potential roles for this technology in the management of patients with pancreatic cancer, including screening, diagnosis, prognosis and monitoring of treatment efficacy; however based on current available evidence they are not yet ready for routine clinical practice.
Publish Date	2016-08-24 10:09
Citation	Lewis AR, Valle JW, McNamara MG. Pancreatic cancer: Are “liquid biopsies” ready for prime-time? World J Gastroenterol 2016; 22(32): 7175-7185
URL	http://www.wjgnet.com/1007-9327/full/v22/i32/7175.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i32.7175

Full Article (PDF)	WJG-22-7175.pdf
Full Article (Word)	WJG-22-7175.doc
Manuscript File	26804-Review.doc
Answering Reviewers	26804-Answering reviewers.pdf
Audio Core Tip	26804-Audio core tip.wav
Conflict-of-Interest Disclosure Form	26804-Conflict-of-interest statement.pdf
Copyright License Agreement	26804-Copyright assignment.pdf
Peer-review Report	26804-Peer-review(s).pdf
Scientific Misconduct Check	26804-Scientific misconduct check.pdf
Scientific Editor Work List	26804-Scientific editor work list.pdf