Publication Name	World Journal of Stem Cells
Manuscript ID	26818
Country	Japan

Received	2016-04-28 15:18
Peer-Review Started	2016-04-28 15:33
To Make the First Decision	2016-06-12 09:24
Return for Revision	2016-06-16 11:28
Revised	2016-07-12 17:28
Second Decision	2016-07-14 15:01
Accepted by Journal Editor-in-Chief	2016-07-14 17:04
Accepted by Executive Editor-in-Chief	2016-07-22 11:25
Articles in Press	2016-07-22 11:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-09-13 13:17
Publish the Manuscript Online	2016-09-19 15:28

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Biology
Manuscript Type	Minireviews
Article Title	Roles and regulation of bone morphogenetic protein-7 in kidney development and diseases
Manuscript Source	Invited Manuscript
All Author List	Taro Tsujimura, Mana Idei, Masahiro Yoshikawa, Osamu Takase and Keiichi Hishikawa
Funding Agency and Grant Number	Funding Agency Grant Number Grants-in-Aid for Young Scientists (B) from the Japan Society for the Promotion of Science 15K18454 (to Tsujimura T) Grants-in-Aid for Scientific Research (B) from the Japan Society for the Promotion of Science 15H03001 (to Hishikawa K) Grants-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science 25461208 (to Takase O) Grants-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science 15K09244 (to Yoshikawa M) Grants-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science 26462400 (to Idei M)
Corresponding Author	Keiichi Hishikawa, MD, PhD, Department of Advanced Nephrology and Regenerative Medicine, Division of Tissue Engineering, University of Tokyo Hospital, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655, Japan. hishikawa-tky@umin.ac.jp
Key Words	Bone morphogenetic protein-7; Therapeutics; Kidney; Development; Nephron progenitor cells; Disease; Regeneration; Chromatin conformation; Gene expression; Gene regulation
Core Tip	Bone morphogenetic protein-7 (BMP7) plays crucial roles in both the development and regeneration of the kidney. The functions and mechanisms of this protein have been clarified extensively for these processes in the fetus and adult kidney. However, the functional differences of BMP7 secreted from different sites in the kidney remain undefined. We propose that uncovering the regulatory mechanism underlying BMP7 expression will help to solve that issue. Moreover, those data should pave the way towards development of a novel therapeutic strategy for kidney diseases via hyperactivation of the endogenous action of BMP7.
Publish Date	2016-09-19 15:28
Citation	Tsujimura T, Idei M, Yoshikawa M, Takase O, Hishikawa K. Roles and regulation of bone morphogenetic protein-7 in kidney development and diseases. World J Stem Cells 2016; 8(9): 288-296
URL	http://www.wjgnet.com/1948-0210/full/v8/i9/288.htm
DOI	http://dx.doi.org/10.4252/wjsc.v8.i9.288

Full Article (PDF)	WJSC-8-288.pdf
Full Article (Word)	WJSC-8-288.doc
Manuscript File	26818-Review.docx
Answering Reviewers	26818-Answering reviewers.pdf
Audio Core Tip	26818-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	26818-Conflict-of-interest statement.pdf
Copyright License Agreement	26818-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	26818-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	26818-Language certificate.pdf
Peer-review Report	26818-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	26818-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	26818-Scientific misconduct check.pdf
Scientific Editor Work List	26818-Scientific editor work list.pdf