Publication Name	World Journal of Cardiology
Manuscript ID	26828
Country	Germany

Received	2016-04-28 15:56
Peer-Review Started	2016-04-28 22:48
To Make the First Decision	2016-06-12 09:25
Return for Revision	2016-06-16 11:42
Revised	2016-06-21 19:09
Second Decision	2016-07-05 17:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-07-18 10:48
Articles in Press	2016-07-18 10:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-10 14:20
Publish the Manuscript Online	2016-08-22 14:58

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Review
Article Title	Renal sympathetic denervation in therapy resistant hypertension - pathophysiological aspects and predictors for treatment success
Manuscript Source	Invited Manuscript
All Author List	Karl Fengler, Karl Philipp Rommel, Thomas Okon, Gerhard Schuler and Philipp Lurz
Funding Agency and Grant Number
Corresponding Author	Philipp Lurz, MD, PhD, Department of Internal Medicine/Cardiology, University of Leipzig - Heart Center, Strümpellstraße 39, 04289 Leipzig, Germany. philipp.lurz@gmx.de
Key Words	Renal sympathetic denervation; Sympathetic nervous system; Predictors; Hypertension; Renal hypertension
Core Tip	The initial enthusiasm for renal sympathetic denervation (RDN) has disappeared. However, the detailed effects of RDN on the complex pathophysiological mechanisms underlying therapy resistant hypertension are only partly understood and are part of ongoing research. Moreover, a number of promising predictors for successful RDN treatment have been identified recently which could help to improve future trial design. This review summarizes important pathophysiologic effects of renal denervation and illustrates the currently known predictors for therapy success.
Publish Date	2016-08-22 14:58
Citation	Fengler K, Rommel KP, Okon T, Schuler G, Lurz P. Renal sympathetic denervation in therapy resistant hypertension - pathophysiological aspects and predictors for treatment success. World J Cardiol 2016; 8(8): 436-446
URL	http://www.wjgnet.com/1949-8462/full/v8/i8/436.htm
DOI	http://dx.doi.org/10.4330/wjc.v8.i8.436

Full Article (PDF)	WJC-8-436.pdf
Full Article (Word)	WJC-8-436.doc
Manuscript File	26828-Review.docx
Answering Reviewers	26828-Answering reviewers.pdf
Audio Core Tip	26828-Audio core tip.wav
Conflict-of-Interest Disclosure Form	26828-Conflict-of-interest statement.pdf
Copyright License Agreement	26828-Copyright assignment.pdf
Peer-review Report	26828-Peer-review(s).pdf
Scientific Misconduct Check	26828-Scientific misconduct check.pdf
Scientific Editor Work List	26828-Scientific editor work list.pdf