Publication Name	World Journal of Gastroenterology
Manuscript ID	26929
Country	United States

Received	2016-04-29 16:01
Peer-Review Started	2016-05-04 14:40
To Make the First Decision	2016-07-13 13:30
Return for Revision	2016-07-18 08:51
Revised	2016-08-03 19:40
Second Decision	2016-08-10 17:53
Accepted by Journal Editor-in-Chief	2016-08-13 10:46
Accepted by Executive Editor-in-Chief	2016-08-23 17:28
Articles in Press	2016-08-23 17:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-09-23 11:38
Publish the Manuscript Online	2016-09-30 18:06

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Hepatocellular carcinoma in patients with non-alcoholic fatty liver disease
Manuscript Source	Invited Manuscript
All Author List	Carrie R Wong, Mindie H Nguyen and Joseph K Lim
Funding Agency and Grant Number
Corresponding Author	Joseph K Lim, MD, Associate Professor, Yale Liver Center, Section of Digestive Diseases, Yale University School of Medicine, 333 Cedar Street, LMP 1080, New Haven, CT 06520, United States. joseph.lim@yale.edu
Key Words	Fatty liver; Nonalcoholic steatohepatitis; Hepatocellular carcinoma; Liver cirrhosis; Liver cancer
Core Tip	This review summarizes the epidemiology, pathogenesis, disease presentation, demand and receipt of curative treatment, and post-treatment outcomes of hepatocellular carcinoma (HCC) in nonalcoholic fatty liver disease (NAFLD). The review highlights the developing understanding of NAFLD-HCC pathogenesis, which has broadened to include genetic polymorphisms, adaptive immune responses, and cellular regenerative pathways using hepatic progenitor cell populations. While NAFLD-HCC has been described to have poorer prognosis as compared with other HCC etiologies, this review features summarized evidence that disease-free and survival rates among patients with NAFLD-HCC are comparable and potentially favorable after receipt of curative treatment.
Publish Date	2016-09-30 18:06
Citation	Wong CR, Nguyen MH, Lim JK. Hepatocellular carcinoma in patients with non-alcoholic fatty liver disease. World J Gastroenterol 2016; 22(37): 8294-8303
URL	http://www.wjgnet.com/1007-9327/full/v22/i37/8294.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i37.8294

Full Article (PDF)	WJG-22-8294.pdf
Full Article (Word)	WJG-22-8294.doc
Manuscript File	26929-Review.docx
Answering Reviewers	26929-Answering reviewers.pdf
Audio Core Tip	26929-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	26929-Conflict-of-interest statement.pdf
Copyright License Agreement	26929-Copyright assignment.pdf
Supplementary Material	Supplementary_Material_20160429155709.docx
Peer-review Report	26929-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	26929-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	26929-Scientific misconduct check.pdf
Scientific Editor Work List	26929-Scientific editor work list.pdf