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Articles Published Processes
9/22/2016 9:52:00 AM | Browse: 1268 | Download: 2158
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Received |
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2016-05-02 18:03 |
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Peer-Review Started |
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2016-05-03 14:15 |
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To Make the First Decision |
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2016-06-12 09:38 |
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Return for Revision |
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2016-06-17 16:44 |
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Revised |
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2016-07-13 06:15 |
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Second Decision |
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2016-08-08 15:30 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2016-08-18 11:54 |
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Articles in Press |
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2016-08-18 11:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-09-18 11:53 |
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Publish the Manuscript Online |
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2016-09-22 09:52 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ilaria Croci, Nuala M Byrne, Veronique S Chachay, Andrew P Hills, Andrew D Clouston, Trisha M O’Moore-Sullivan, Johannes B Prins, Graeme A Macdonald and Ingrid J Hickman |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Health and Medical Research Council of Australia |
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| Lions Medical Research Foundation |
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| Corresponding Author |
Ilaria Croci, PhD, School of Human Movement and Nutrition Sciences, University of Queensland, Blair Drive, St. Lucia 4072, Australia. ilaria.croci@uqconnect.edu.au |
| Key Words |
Non-alcoholic steatohepatitis; Steatosis; Fat and carbohydrate oxidation; Exercise; Fitness; Beta-hydroxybutyrate; Ketone bodies; Fatty acid oxidation |
| Core Tip |
We investigated hepatic fat oxidation and whole-body substrate oxidation under basal, insulin-stimulated and exercise conditions before and after 6 mo of circuit exercise training (EX) or dietary energy restriction (ER) in patients with non-alcoholic fatty liver disease. ER increased β-hydroxybutyrate concentrations (a marker of hepatic fat oxidation) and reduced severity of steatosis, but did not change substrate oxidation rates during acute exercise. EX improved substrate oxidation under basal, insulin-stimulated and exercise conditions, but not β-hydroxybutyrate concentrations and severity of disease. Increase in β-hydroxybutyrate was associated with decrease in hepatic steatosis and this could be one mechanism through which the ER group achieved reduc-tion in steatosis. |
| Publish Date |
2016-09-22 09:52 |
| Citation |
Croci I, Byrne NM, Chachay VS, Hills AP, Clouston AD, O’Moore-Sullivan TM, Prins JB, Macdonald GA, Hickman IJ. Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease. World J Hepatol 2016; 8(27): 1137-1148 |
| URL |
http://www.wjgnet.com/1948-5182/full/v8/i27/1137.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v8.i27.1137 |
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