Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	26986
Country	Türkiye

Received	2016-05-03 09:29
Peer-Review Started	2016-05-03 13:15
To Make the First Decision	2016-06-06 17:17
Return for Revision	2016-06-07 14:38
Revised	2016-06-17 18:30
Second Decision	2016-07-04 17:11
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-07-18 10:58
Articles in Press	2016-07-18 10:58
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-08-09 16:35
Typeset the Manuscript	2016-08-31 11:08
Publish the Manuscript Online	2016-09-12 10:43

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Mehmet Mihmanlı, Esin Kabul Gürbulak, İsmail Ethem Akgün, Mustafa Fevzi Celayir, Pınar Yazıcı, Deniz Tunçel, Tuba Tülin Bek, Ayhan Öz and Sinan Ömeroğlu
Funding Agency and Grant Number
Corresponding Author	Esin Kabul Gürbulak, MD, Department of General Surgery, Şişli Etfal Training and Research Hospital, Halaskargazi Cad, Etfal Sk, Şişli 34371, Istanbul, Turkey. ekabul@gmail.com
Key Words	Rectal carcinoma; Pathological tumor response; Neoadjuvant chemoradiotherapy; Interval timing; Tumor down-staging
Core Tip	Delaying the neoadjuvant chemoradiotherapy (CRT)-surgery interval for treatment of locally advanced rectal carcinoma may improve pathological complete response rates by providing nodal down-staging, as well as decreasing the rate of tumor regression grade (TRG) poor response. TRG may be an important predictive factor for disease-free survival. Extending the interval between CRT and surgery may improve the survival through tumor down-staging without increasing the rate of surgical complications.
Publish Date	2016-09-12 10:43
Citation	Mihmanlı M, Kabul Gürbulak E, Akgün İE, Celayir MF, Yazıcı P, Tunçel D, Bek TT, Öz A, Ömeroğlu S. Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer. World J Gastrointest Oncol 2016; 8(9): 695-706
URL	http://www.wjgnet.com/1948-5204/full/v8/i9/695.htm
DOI	http://dx.doi.org/10.4251/wjgo.v8.i9.695

Full Article (PDF)	WJGO-8-695.pdf
Full Article (Word)	WJGO-8-695.doc
Manuscript File	26986-Review.doc
Answering Reviewers	26986-Answering reviewers.pdf
Audio Core Tip	26986-Audio core tip.mp3
Biostatistics Review Certificate	26986-Bioistatistics statement.pdf
Conflict-of-Interest Disclosure Form	26986-Conflict-of-interest statement.pdf
Copyright License Agreement	26986-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160503061717.docx
Institutional Review Board Approval Form or Document	26986-Institutional review board statement.pdf
Peer-review Report	26986-Peer-review(s).pdf
Scientific Misconduct Check	26986-Scientific misconduct check.pdf
Scientific Editor Work List	26986-Scientific editor work list.pdf