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10/20/2016 5:06:00 PM | Browse: 882 | Download: 1233
Publication Name World Journal of Gastroenterology
Manuscript ID 27013
Country Italy
Received
2016-05-05 09:37
Peer-Review Started
2016-05-05 11:38
To Make the First Decision
2016-05-27 11:09
Return for Revision
2016-05-27 15:33
Revised
2016-06-30 16:34
Second Decision
2016-07-19 12:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-08-01 15:40
Articles in Press
2016-08-01 15:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-10-13 11:20
Publish the Manuscript Online
2016-10-20 17:06
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Comparison of magnetic resonance spectroscopy, proton density fat fraction and histological analysis in the quantification of liver steatosis in children and adolescents
Manuscript Source Unsolicited Manuscript
All Author List Michele Di Martino, Lucia Pacifico, Mario Bezzi, Rossella Di Miscio, Beatrice Sacconi, Claudio Chiesa and Carlo Catalano
Funding Agency and Grant Number
Corresponding Author Michele Di Martino, PhD, MD, Department of Radiological Sciences, Oncology and Anatomical Pathology, “Sapienza” University of Rome, V.le Regina Elena 324, 00161 Roma, Italy. micdimartino@hotmail.it
Key Words Magnetic resonance spectroscopy; Magnetic resonance imaging-PDFF; Obesity; Non-alcoholic fatty liver disease; Children
Core Tip Differentiating normal from pathologic liver fat storage in children could depend on technical measurements. Using MR-spectroscopy, a cut-off value of 6% demonstrates the best diagnostic performance, otherwise magnetic resonance imaging (MRI)-PDFF cut-off value of 3.5% better discriminates normal weight from obese children. It is confirmed that MRS is an accurate and precise method for detecting non-alcoholic fatty liver disease in children. However, MRI-PDFF- is a feasible alternative to MRS for quantifying liver steatosis.
Publish Date 2016-10-20 17:06
Citation Di Martino M, Pacifico L, Bezzi M, Di Miscio R, Sacconi B, Chiesa C, Catalano C. Comparison of magnetic resonance spectroscopy, proton density fat fraction and histological analysis in the quantification of liver steatosis in children and adolescents. World J Gastroenterol 2016; 22(39): 8812-8819
URL http://www.wjgnet.com/1007-9327/full/v22/i39/8812.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i39.8812
Full Article (PDF) WJG-22-8812.pdf
Full Article (Word) WJG-22-8812.doc
Manuscript File 27013-Review.doc
Answering Reviewers 27013-Answering reviewers.pdf
Audio Core Tip 27013-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 27013-Conflict-of-interest statement.pdf
Copyright License Agreement 27013-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160504194252.doc
Institutional Review Board Approval Form or Document 27013-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 27013-Language certificate.pdf
Peer-review Report 27013-Peer-review(s).pdf
Scientific Misconduct Check 27013-Scientific misconduct check.pdf
Scientific Editor Work List 27013-Scientific editor work list.pdf