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9/4/2016 2:49:00 PM | Browse: 944 | Download: 1909
Publication Name World Journal of Gastroenterology
Manuscript ID 27026
Country/Territory South Korea
Received
2016-05-05 15:53
Peer-Review Started
2016-05-06 11:23
To Make the First Decision
2016-06-20 10:51
Return for Revision
2016-06-27 17:01
Revised
2016-07-11 21:35
Second Decision
2016-07-19 12:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-08-01 15:40
Articles in Press
2016-08-01 15:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-08-26 08:58
Publish the Manuscript Online
2016-09-04 14:49
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/ licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Basic Study
Article Title Melatonin modulates adiponectin expression on murine colitis with sleep deprivation
Manuscript Source Invited Manuscript
All Author List Tae Kyun Kim, Young Sook Park, Haing-Woon Baik, Jin Hyun Jun, Eun Kyung Kim, Jae Woong Sull, Ho Joong Sung, Jin Woo Choi, Sook Hee Chung, Myung Chan Gye, Ju Yeon Lim, Jun Bong Kim and Seong Hwan Kim
Funding Agency and Grant Number
Corresponding Author Young Sook Park, MD, PhD, Department of Gastroenterology, Eulji University School of Medicine, Eulji Hospital, 68 Hangeulbiseok-Ro, Nowon-Gu, Seoul 139-711, South Korea. pys1109@eulji.ac.kr
Key Words Colitis; Melatonin; Adiponectin; Sleep deprivation
Core Tip We report this first study that melatonin and sleep deprivation are related to adiponectin expression in the colonic mucosa of murine colitis. C57BL/6 mice were feeding with 2% DSS for inducing colitis and using specially designed multiple platform water baths for sleep deprivation. Immuno-histochemical staining and Western blot analysis was performed using anti-adiponectin antibody. The expression level of adiponectin in mucosa was decreased in colitis, with the lowest level observed in colitis combined with sleep deprivation. Melatonin injection significantly (P < 0.05) recovered the expression of adiponectin. This study suggests that melatonin and adiponectin synergistically potentiate the anti-inflammatory effects in murine colitis.
Publish Date 2016-09-04 14:49
Citation Kim TK, Park YS, Baik HW, Jun JH, Kim EK, Sull JW, Sung HJ, Choi JW, Chung SH, Gye MC, Lim JY, Kim JB, Kim SH. Melatonin modulates adiponectin expression on murine colitis with sleep deprivation. World J Gastroenterol 2016; 22(33): 7559-7568
URL http://www.wjgnet.com/1007-9327/full/v22/i33/7559.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i33.7559
Full Article (PDF) WJG-22-7559.pdf
Full Article (Word) WJG-22-7559.doc
Manuscript File 27026-Review.doc
Answering Reviewers 27026-Answering review(s).pdf
Audio Core Tip 27026-Audio core tip.mp3
Biostatistics Review Certificate 27026-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 27026-Conflict-of-interest statement.pdf
Copyright License Agreement 27026-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 27026-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 27026-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 27026-Language certificate.pdf
Peer-review Report 27026-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 27026-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 27026-Scientific misconduct check.pdf
Scientific Editor Work List 27026-Scientific editor work list.pdf