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Articles Published Processes
10/12/2016 2:18:00 PM | Browse: 1190 | Download: 2149
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Received |
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2016-05-06 09:32 |
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Peer-Review Started |
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2016-05-06 11:51 |
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To Make the First Decision |
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2016-06-20 10:51 |
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Return for Revision |
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2016-06-27 17:03 |
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Revised |
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2016-07-04 13:26 |
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Second Decision |
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2016-07-19 12:14 |
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Accepted by Journal Editor-in-Chief |
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2016-07-21 20:13 |
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Accepted by Executive Editor-in-Chief |
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2016-08-01 15:42 |
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Articles in Press |
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2016-08-01 15:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-09-27 11:17 |
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Publish the Manuscript Online |
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2016-10-12 14:18 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Pancreatic neuroendocrine tumor and solid-pseudopapillary neoplasm: Key immunohistochemical profiles for differential diagnosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yusuke Ohara, Tatsuya Oda, Shinji Hashimoto, Yoshimasa Akashi, Ryoichi Miyamoto, Tsuyoshi Enomoto, Kaishi Satomi, Yukio Morishita and Nobuhiro Ohkohchi |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Scientific Research KAKENHI |
23300362 |
| Scientific Research KAKENHI |
23659635 |
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| Corresponding Author |
Tatsuya Oda, MD, PhD, Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan. tatoda@md.tsukuba.ac.jp |
| Key Words |
Neuroendocrine tumor; Pancreas; Solid-pseudopapillary neoplasm; Immunohistochemistry; Diagnosis |
| Core Tip |
Neuroendocrine tumor (NET) and solid-pseudopapillary neoplasm (SPN) are two types of pancreatic tumor that were sometimes confused in differential diagnosis. We reviewed 30 pancreatic surgical specimens of NET (24 cases) and SPN (6 cases). We carried out comprehensive immunohistochemical profiling using 9 markers. E-cadherin staining in NETs, and nuclear labeling of β-catenin in SPNs were the most sensitive and specific markers. Dot-like staining of chromogranin A might indicate the possibility of SPNs rather than NETs. Moreover, two cases that had been initially diagnosed as NETs on the basis of their morphological features, demonstrated SPN-like immunohistochemical profiles. |
| Publish Date |
2016-10-12 14:18 |
| Citation |
Ohara Y, Oda T, Hashimoto S, Akashi Y, Miyamoto R, Enomoto T, Satomi K, Morishita Y, Ohkohchi N. Pancreatic neuroendocrine tumor and solid-pseudopapillary neoplasm: Key immunohistochemical profiles for differential diagnosis. World J Gastroenterol 2016; 22(38): 8596-8604 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i38/8596.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i38.8596 |
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