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Articles Published Processes
9/4/2016 2:49:00 PM | Browse: 1174 | Download: 2118
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Received |
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2016-05-08 13:32 |
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Peer-Review Started |
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2016-05-08 20:24 |
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To Make the First Decision |
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2016-06-20 10:52 |
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Return for Revision |
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2016-06-28 09:20 |
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Revised |
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2016-06-29 20:53 |
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Second Decision |
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2016-07-07 10:07 |
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Accepted by Journal Editor-in-Chief |
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2016-07-07 11:05 |
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Accepted by Executive Editor-in-Chief |
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2016-07-21 16:03 |
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Articles in Press |
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2016-07-21 16:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-08-26 08:55 |
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Publish the Manuscript Online |
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2016-09-04 14:49 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was
selected by an in-house editor and fully peer-reviewed by external
reviewers. It is distributed in accordance with the Creative
Commons Attribution Non Commercial (CC BY-NC 4.0) license,
which permits others to distribute, remix, adapt, build upon this
work non-commercially, and license their derivative works on
different terms, provided the original work is properly cited and
the use is non-commercial. See: http://creativecommons.org/
licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2016. Published by Baishideng Publishing
Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Infectious Diseases |
Manuscript Type |
Basic Study |
Article Title |
Impact of Helicobacter pylori on the healing process of the gastric barrier
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Manuscript Source |
Invited Manuscript |
All Author List |
Eliza Mnich, Magdalena Kowalewicz-Kulbat, Paulina Sicińska, Krzysztof Hinc, Michał Obuchowski, Adrian Gajewski, Anthony P Moran and Magdalena Chmiela |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Science Centre of Poland |
DEC-2013/09/N/NZ6/00805 |
National Science Centre of Poland |
DEC-2015/17/N/NZ6/03490 |
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Corresponding Author |
Magdalena Chmiela, Professor, PhD, Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland. chmiela@biol.uni.lodz.pl |
Key Words |
Helicobacter pylori; Wound healing; Gastric barrier dysfunction |
Core Tip |
This manuscript focused on the impact of Helicobacter pylori (H. pylori) antigens to the gastric mucosal barrier. We evaluated the effects of H. pylori antigens using in vitro two cellular models of gastric epithelial cells and fibroblasts, which had been independently exposed to H. pylori components. In this study, we showed different effects of subunit A of urease, cytotoxin associated gene A protein, lipopolysaccharide (LPS) as well as compounds included in a glycine acid extract on the regenerative activity of gastric epithelial cells and fibroblasts. Our results indicate deleterious, dose dependent influence of H. pylori LPS on this process. |
Publish Date |
2016-09-04 14:49 |
Citation |
Mnich E, Kowalewicz-Kulbat M, Sicińska P, Hinc K, Obuchowski M, Gajewski A, Moran AP, Chmiela M. Impact of Helicobacter pylori on the healing process of the gastric barrier. World J Gastroenterol 2016; 22(33): 7536-7558 |
URL |
http://www.wjgnet.com/1007-9327/full/v22/i33/7536.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v22.i33.7536 |
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