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Articles Published Processes
12/13/2016 12:40:00 AM | Browse: 944 | Download: 1716
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Received |
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2016-06-21 10:50 |
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Peer-Review Started |
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2016-06-22 09:04 |
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To Make the First Decision |
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2016-07-29 15:14 |
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Return for Revision |
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2016-07-29 18:25 |
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Revised |
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2016-08-25 23:34 |
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Second Decision |
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2016-09-21 17:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-09-28 19:15 |
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Articles in Press |
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2016-09-28 19:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2016-10-26 16:05 |
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Typeset the Manuscript |
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2016-11-25 16:47 |
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Publish the Manuscript Online |
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2016-12-13 00:40 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Effect of switching from treatment with nucleos(t)ide analogs to pegylated interferon α-2a on virological and serological responses in chronic hepatitis B patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Ting He, Xiao-Guang Ye and Xiao-Yuan Zhou |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Xiao-Guang Ye, Department of In fectious Diseases, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, Guangdong Province, China. yexiaoguang@126.com |
| Key Words |
Chronic hepatitis B; Entecavir; pegylated interferon-α-2a; Sequential therapy; Effect |
| Core Tip |
It is necessary to achieve termination safely with minimal risk of long-term resistance in nucleos(t)ide analog (NA)-treated chronic hepatitis B (CHB) patients. We studied NA-treated CHB patients who stopped NAs safely and achieved sustained virological and immunological responses after treatment. We clarified the efficacy and safety of sequential 48-wk pegylated interferon-α-2a (PegIFNα-2a) in NA-treated CHB patients during and after treatment termination. Patients were selected based on the initial serum hepatitis B surface antigen (HBsAg) level. PegIFNα-2a was adjusted based on HBsAg levels at 24 wk of treatment, an important and significant factor in achieving treatment termination safely with immune control. |
| Publish Date |
2016-12-13 00:40 |
| Citation |
He LT, Ye XG, Zhou XY. Effect of switching from treatment with nucleos(t)ide analogues to pegylated interferon -2a on virological and serological response in chronic hepatitis B patients. World J Gastroenterol 2016; 22(46): 10210-10218 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i46/10210.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i46.10210 |
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