Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	27261
Country	United States

Received	2016-05-20 08:52
Peer-Review Started	2016-05-20 14:36
To Make the First Decision	2016-07-20 16:48
Return for Revision	2016-07-21 11:35
Revised	2016-08-23 07:43
Second Decision	2016-09-07 14:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-09-18 14:36
Articles in Press	2016-09-18 14:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-02 17:43
Publish the Manuscript Online	2016-12-14 09:26

ISSN	1948-5190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Outcomes of submucosal (T1b) esophageal adenocarcinomas removed by endoscopic mucosal resection
Manuscript Source	Invited Manuscript
All Author List	Darren D Ballard, Neel Choksi, Jingmei Lin, Eun-Young Choi, B Joseph Elmunzer, Henry Appelman, Douglas K Rex, Hala Fatima, William Kessler and John M DeWitt
Funding Agency and Grant Number
Corresponding Author	Darren D Ballard, Assistant Professor, Division of Gastroenterology and Hepatology, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI 53226, United States. dballard@mcw.edu
Key Words	Esophageal cancer; Submucosal; T1b; Endoscopic mucosal resection; Chemotherapy; Esophagec­tomy
Core Tip	Endoscopic eradication therapy (EET) is reported as safe and effective for low risk T1b esopha-geal adenocarcinomas (EAC), but overall data is lacking. We retrospectively evaluated patients with T1b EAC treated with EET, EET with chemotherapy and/or radiation therapy and surgical resection. The overall recur-rence rate was 28% at median 21 mo (range: 6-73) following EMR. In those treated with endoscopic mucosal resection alone, recurrence rate was 38% at median 21 mo (range: 6-73). Six of the 9 recurrences were local; 5 were treated with endoscopy alone. EET of T1b EAC may be a reasonable treatment strategy for a subset of these patients.
Publish Date	2016-12-14 09:26
Citation	Ballard DD, Choksi N, Lin J, Choi EY, Elmunzer BJ, Appelman H, Rex DK, Fatima H, Kessler W, DeWitt JM. Outcomes of submucosal (T1b) esophageal adenocarcinomas removed by endoscopic mucosal resection. World J Gastrointest Endosc 2016; 8(20): 763-769
URL	http://www.wjgnet.com/1948-5190/full/v8/i20/763.htm
DOI	http://dx.doi.org/10.4253/wjge.v8.i20.763

Full Article (PDF)	WJGE-8-763.pdf
Full Article (Word)	WJGE-8-763.doc
Manuscript File	27261-Review.docx
Answering Reviewers	27261-Answering reviewers.pdf
Audio Core Tip	27261-Audio core tip.m4a
Biostatistics Review Certificate	27261-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	27261-Conflict-of-interest statement.pdf
Copyright License Agreement	27261-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	27261-Institutional review board statement.pdf
Peer-review Report	27261-Peer-review(s).pdf
Scientific Misconduct Check	27261-Scientific misconduct check.pdf
Scientific Editor Work List	27261-Scientific editor work list.pdf